Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC4 E): the ALIC4 E protocol

Emily Bongard; Alike W van der Velden; Johanna Cook; Ben Saville; Philippe Beutels; Rune Munck Aabenhus; Curt Brugman; Slawomir Chlabicz; Samuel Coenen; Annelies Colliers; Melanie Davies; Muireann De Paor; An De Sutter; Nick A Francis; Dominik Glinz; Maciek Godycki-ćwirko; Herman Goossens; Jane Holmes; Margareta Ieven; Menno de Jong; Morten Lindbaek; Paul Little; Frederico Martinón-Torres; Ana Moragas; József Pauer; Markéta Pfeiferová; Ruta Radzeviciene-Jurgute; Pär-Daniel Sundvall; Antoni Torres; Pia Touboul; Dionyssios Varthalis; Theo Verheij; Christopher C Butler

doi:10.1136/bmjopen-2017-021032

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General practice / Family practice

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Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC⁴ E): the ALIC⁴ E protocol

Authors

Emily Bongard The Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Alike W van der Velden Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands PubMed articles Google scholar articles
Johanna Cook The Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Ben Saville Berry Consultants, Austin, Texas, USA Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA PubMed articles Google scholar articles
Philippe Beutels Centre for Health Economics Research and Modelling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium PubMed articles Google scholar articles
Rune Munck Aabenhus Institute for Public Health, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Curt Brugman Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands PubMed articles Google scholar articles
Slawomir Chlabicz Department of Family Medicine and Community Nursing, Medical University of Bialystok, Bialystok, Poland PubMed articles Google scholar articles
Samuel Coenen Centre for General Practice, Department of Primary and Interdisciplinary Care (ELIZA), University of Antwerp, Antwerp, Belgium Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium PubMed articles Google scholar articles
Annelies Colliers Centre for General Practice, Department of Primary and Interdisciplinary Care (ELIZA), University of Antwerp, Antwerp, Belgium PubMed articles Google scholar articles
Melanie Davies Ely Bridge Surgery, Ely, UK PubMed articles Google scholar articles
Muireann De Paor Department of General Practice, Royal College of Surgeons in Ireland School of Medicine, Dublin, Ireland PubMed articles Google scholar articles
An De Sutter Department of Family Medicine and Primary Health Care, Ghent University, Ghent, Belgium PubMed articles Google scholar articles
Nick A Francis Department of Population Medicine, Cardiff University School of Medicine, Cardiff, UK PubMed articles Google scholar articles
Dominik Glinz University of Basel, Basel, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland PubMed articles Google scholar articles
Maciek Godycki-ćwirko Department of Family and Community Medicine, Medical University of Lodz, Lodz, Poland PubMed articles Google scholar articles
Herman Goossens Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium PubMed articles Google scholar articles
Jane Holmes Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Margareta Ieven Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium PubMed articles Google scholar articles
Menno de Jong Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
Morten Lindbaek Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway PubMed articles Google scholar articles
Paul Little Primary Care and Population Science, University of Southampton, Southampton, UK PubMed articles Google scholar articles
Frederico Martinón-Torres SERGAS, Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela, Spain PubMed articles Google scholar articles
Ana Moragas Primary Healthcare Centre Jaume I, Universitat Rovira i Virgili, Tarragona, Catalonia, Spain PubMed articles Google scholar articles
József Pauer Drug Research Centre LLC, Balatonfüred, Hungary PubMed articles Google scholar articles
Markéta Pfeiferová Institute of General Practice, First Faculty of Medicine, Charles University, Prague, Czech Republic PubMed articles Google scholar articles
Ruta Radzeviciene-Jurgute JSC Mano Seimos Gydytojas, Klaipėda, Lithuania PubMed articles Google scholar articles
Pär-Daniel Sundvall Närhälsan, Research and Development Primary Health Care, Region Västra Götaland, Research and Development Center Södra Älvsborg, Borås, Sweden Department of Public Health and Community Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden PubMed articles Google scholar articles
Antoni Torres Department of Pulmonology, Hospital Clínic de Barcelona, Universitat de Barcelona and IDIBAPS, Barcelona, Spain PubMed articles Google scholar articles
Pia Touboul Department of Public Health, University Hospital of Nice, Nice, France Department of Teaching and Research in General Practice, University of Côte d’Azur, Nice, France PubMed articles Google scholar articles
Dionyssios Varthalis Clinic of Social and Family Medicine, University of Crete, Heraklion, Greece PubMed articles Google scholar articles
Theo Verheij Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands PubMed articles Google scholar articles
Christopher C Butler The Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK PubMed articles Google scholar articles

Correspondence to Dr Emily Bongard; emily.bongard{at}phc.ox.ac.uk

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Citation

Bongard E, van der Velden AW, Cook J, et al

Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC⁴ E): the ALIC⁴ E protocol

BMJ Open 2018;8:e021032. doi: 10.1136/bmjopen-2017-021032

Publication history

Received December 8, 2017
Revised May 1, 2018
Accepted June 14, 2018
First published July 12, 2018.

Online issue publication

January 10, 2022

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© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:©http://creativecommons.org/licenses/by-nc/4.0/.

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