Aim To investigate the characteristics of young adult cataract (YAC) patients over a 10-year period.
Methods This observational study included YAC patients aged 18–49 years who were treated surgically for the first time at the Zhongshan Ophthalmic Center in China. YAC patients were analysed and compared with patients with childhood cataract (CC) in January 2005 to December 2014.
Results During the 10-year period, 515 YAC patients and 2421 inpatients with CC were enrolled. Among the YAC patients, 76.76% (109/142) of unilateral patients had a corrected distance visual acuity (CDVA) better than 20/40 in the healthy eye, whereas only 20.38% (76/373) of bilateral patients had a CDVA better than 20/40 in the eye with better visual acuity. Compared with the CC group, the YAC group had a higher proportion of rural patients (40.40% vs 31.60%, p=0.001). Furthermore, the prevalence of other ocular abnormalities in YAC patients was higher than that in patients with CC (29.71% vs 17.47%, p<0.001).
Conclusions A large proportion coming from rural areas and a high prevalence of complicated ocular abnormalities may be the most salient characteristics of YAC patients. Strengthening the counselling and screening strategy for cataract and health education for young adults are required especially for those in rural areas.
- young adult cataract
- childhood cataract
- clinical characteristic
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DL and ZL contributed equally.
Contributors HL, DL, WC and YL contributed to the conception or design of the work. ZLiu, QC, XW, JLiu, JC, ZLin and XL contributed to the acquisition of data. LZ, EL, XZha and JW contributed to the analysis. DW, XZ, TY, JLi, XZhao and LW contributed to the interpretation of data for the work. HL and DL contributed to drafting the work and critical revision for important intellectual content. All authors gave final approval of the version to be published.
Funding This clinical study was supported by the NSFC (81270980, 81300750), the Guangdong Provincial Natural Science Foundation for Distinguished Young Scholars of China (2014A030306030), and the Clinical Research and Translational Medical Center of Pediatric Cataract in Guangzhou City (201505032017516). The sponsors of the study played no role in the study protocol design, data collection, data analysis, data interpretation, manuscript preparation or the decision to submit the manuscript for publication.
Competing interests None declared.
Patient consent Not required.
Ethics approval All procedures in our series of ongoing cataract studies were consistent with the tenets of the Declaration of Helsinki and were approved by the Ethical Review Committee of the Zhongshan Ophthalmic Center in Sun Yat-sen University (ERC-ZOC-SYSU). Due to the retrospective nature of the study, written informed consent was waived by the ERC.
Provenance and peer review Not commissioned; externally peer reviewed.
Data sharing statement All of the data are in the manuscript, and no additional data are available.
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