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Cardiovascular medicine
Cohort profile
Cohort profile: the Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort
  1. Maria Wanitschek1,
  2. Michael Edlinger2,
  3. Jakob Dörler1,
  4. Hannes F Alber3,4
  1. 1 University Clinic of Internal Medicine III - Cardiology and Angiology, Medical University of Innsbruck, Innsbruck, Austria
  2. 2 Department of Medical Statistics, Informatics, and Health Economics, Medical University of Innsbruck, Innsbruck, Austria
  3. 3 Department of Internal Medicine and Cardiology, Clinic Klagenfurt at Wörthersee, Klagenfurt, Austria
  4. 4 Karl Landsteiner Institute for Interdisciplinary Science, Rehabilitation Centre Münster in Tyrol, Münster, Austria
  1. Correspondence to Dr Michael Edlinger; Michael.Edlinger{at}i-med.ac.at

Abstract

Purpose The Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort is aimed to gain a better understanding of cardiovascular risk factors and their relation to the diagnosis and severity of coronary artery disease, as well as to the long-term prognosis in consecutive (including revascularised) patients referred for elective coronary angiography.

Participants The included patients visited the University Clinic of Cardiology at Innsbruck (Austria), which fulfils a secondary and tertiary hospital function. Inclusion took place in the period between February 2004 and April 2008 and resulted in a total of 8296 patients aged 18–91 years; 65% of them were men.

Findings to date There was one follow-up round on vital status through record linkage for 84% of the cohort (those with residence in Tyrol), resulting in a follow-up duration of over 5.5 to nearly 10.0 years among survivors. The data contain basic patient characteristics, cardiovascular risk factors, laboratory measurements, medications, detailed information on the extent and severity of coronary artery disease, revascularisation history, treatment strategy and mortality specifics. A few studies have already been published.

Future plans Various diagnostic and prognostic studies are planned, also concerning complications, competing risks and cost-effectiveness. Collaboration with other research groups is welcomed.

  • coronary artery disease
  • elective cardiac catheterisation
  • cardiovascular risk factors
  • clinical epidemiology
  • cohort study

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bmjopen-2018-021808

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    Footnotes

    • Contributors HFA, JD and MW initiated the project and coordinated the data entry. MW extracted extra detailed data on the coronary arteries. ME was responsible for data management and preparation. MW wrote the manuscript. HFA is the PI of the CARDIIGAN cohort. HFA, JD and ME revised the manuscript critically. All authors are accountable for this work.

    • Funding CARDIIGAN is an investigator-initiated cohort and no funding was received.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Ethics approval Approval was obtained, for both the original study group and the extension to a cohort with ascertained survival status, from the ethical committee of the Medical University of Innsbruck (UN3266 and AN3266).

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data sharing statement Collaboration is welcomed and data sharing can be agreed upon. The corresponding author can be contacted.