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- Published on: 6 July 2018
- Published on: 25 June 2018
- Published on: 6 July 2018Response to Peter Kemp
Thank you for your letter and sharing the results of your work. We agree on the importance of accurate testing for Lyme disease. In our study, we required that participants have a positive IgG Western blot, a lab result only present at least six to eight weeks after infection, as we were interested in studying patients diagnosed in the later stages of disease. However, as we note in our paper, we recognize that this requirement excluded patients with false-negative laboratory results. Thank you for your comment.
Conflict of Interest:
None declared. - Published on: 25 June 2018Report of VIRAS Survey on Lyme Disease Testing Delay
In the UK and other countries, a major obstacle to the treatment of Lyme Borreliosis is the requirement for positive serology tests. This requirement was incorporated in the recent NICE Guidelines for Lyme Disease (National Institute for Clinical and Care Excellence, NG95 for England and Wales: https://www.nice.org.uk/guidance/ng95).
Although the authors of the guideline claim otherwise, the only concessions which the guideline makes to doctors who wish to treat without positive serology in the absence of a physician diagnosed Erythema Migrans rash, is that they may 'start treatment' whilst awaiting lab results, based on a "high clinical suspicion" - although what form this might take they omit to explain. Neither do they explain what to do when the awaited lab results come back.
Therefore, with up to 75% of cases requiring positive serology to support a diagnosis and treatment, test accuracy is a critical factor in determining who gets treated and who does not, for a potentially injurious infection which all authorities agree, requires prompt diagnosis and treatment.
In January 2018, VIRAS conducted a survey to investigate the reasons and extent of delays before people are tested for Lyme disease. The survey was publicised in Facebook support and campaign groups for Lyme patients and collected 330 responses.
Key points from the survey:
• 78% of respondents indicate...
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None declared.