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  • Systematic review and meta-analysis of the effect of SGLT-2 inhibitors on microvascular outcomes in patients with type 2 diabetes: a review protocol

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Diabetes and endocrinology
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Systematic review and meta-analysis of the effect of SGLT-2 inhibitors on microvascular outcomes in patients with type 2 diabetes: a review protocol
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  • Published on: 4 July 2018
    There is a fundamental but overlooked limitation of this study
    • Sergio Stagnaro, Director Quantum Biophysical Semeiotic Research Laboratory
    • Other Contributors:
      • Simone Caramel, President
      • Marco Marchionni, Vice-President

    The data of such a study are fundamentally biased. As a matter of facts, the Authors do not refer to an essential data: the presence of the CVD Inherited Real Risk of enlisted subjects. To declare the real microvascular outomes in patients with Type 2 Diabetes Mellitus under treatment with SGLT-2, only individuals are to be enrolled, involved by ATS Constitution-Dependent, Inherited Real Risk f CVD. (1-5)

    References.
    1) Stagnaro-Neri M., Stagnaro S., Deterministic Chaos, Preconditioning and Myocardial Oxygenation evaluated clinically with the aid of Biophysical Semeiotics in the Diagnosis of ischaemic Heart Disease even silent. Acta Med. Medit. 13, 109, 1997
    2) Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial Oxygenation and Biophysical-Semeiotic Preconditioning. International Atherosclerosis Society. www.athero.org, 29 April, 2009 http://www.athero.org/commentaries/comm907.asp
    3) Stagnaro Sergio. Role of Coronary Endoarterial Blocking Devices in Myocardial Preconditioning - c007i. Lecture, V Virtual International Congress of Argentine Cardiology. http://www.fac.org.ar/qcvc/llave/c007i/stagnaros.php
    4) Sergio Stagnaro and Simone Caramel. The Inherited R...

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    Conflict of Interest:
    None declared.