Article Text

Download PDFPDF

Association between secondhand smoke exposure and hypertension in never smokers: a cross-sectional survey using data from Korean National Health and Nutritional Examination Survey V, 2010–2012
  1. Young Sik Park1,
  2. Chang-Hoon Lee1,
  3. Yu-Il Kim2,
  4. Chul Min Ahn3,
  5. Ju Ock Kim4,
  6. Ju-Heon Park5,
  7. Sang Haak Lee6,
  8. Jae Yeol Kim7,
  9. Eun Mi Chun8,
  10. Tae-Hoon Jung9,
  11. Kwang-Ha Yoo10
  1. 1 Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
  2. 2 Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea
  3. 3 Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
  4. 4 Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea
  5. 5 Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea
  6. 6 Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
  7. 7 Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
  8. 8 Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea
  9. 9 Department of Internal Medicine, Chilgok Kyungpook National University School of Medicine, Daegu, Korea
  10. 10 Department of Internal Medicine, Konkuk University College of Medicine, Seoul, Korea
  1. Correspondence to Professor Chang-Hoon Lee; kauri670{at}


Objectives Secondhand smoke (SHS) exposure is associated with cardiovascular disease. This study aims to determine the association between SHS exposure estimated by questionnaire and hypertension in Korean never smokers.

Setting Korean National Health and Nutrition Examination Survey (KNHANES) V was conducted from 2010 to 2012.

Participants We selected the never smokers aged over 20 years who answered the question about the SHS exposure.

Primary and secondary measures SHS exposure in both the home and work place was estimated using a self-reporting questionnaire. We investigated the association between SHS exposure and hypertension by using multivariate analysis. And we evaluated the mean systolic and diastolic blood pressure values according to SHS exposure after adjusting for possible confounding factors. All analyses were stratified by women and men.

Results There were 10 532 (women 8987 and men 1545) never smokers. We divided the subjects into three groups according to the amount of SHS exposure: none—group I, <2 hour/day—group II and ≥2 hour/day—group III. Using multivariate analysis, hypertension was more commonly associated with group III than group I in women (adjusted OR 1.50, 95% CI 1.00 to 2.04, p=0.011). Adjusted mean systolic and diastolic blood pressure values in women who were not taking antihypertensive medication were significantly elevated in group III by 2.3 and 1.7 mm Hg, respectively.

Conclusion SHS exposure is significantly associated with hypertension in women never smokers.

  • second-hand smoke
  • hypertension
  • blood pressure
  • knhanes

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:

View Full Text

Statistics from


  • Contributors YSP and C-HL contributed to the conceptualisation. YSP, C-HL and Y-IL were responsible for the data curation. YSP, C-HL and K-HY were responsible for the methodology. C-HL was involved in the project administration. YSP and C-HL drafted the original manuscript. All authors contributed to the review and editing.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Ethics approval Seoul National University Hospital IRB.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement The original data came from Korean National Health and Nutritional Examination Survey ( All the data presented in this manuscript are available from the corresponding author at

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.