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Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis

Authors

  • Gowri Raman Center for Clinical Evidence Synthesis, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, MA, USA PubMed articlesGoogle scholar articles
  • Ethan M Balk Center for Evidence Synthesis in Health, School of Public Health, Brown University, Providence, Rhode Island, USA PubMed articlesGoogle scholar articles
  • Lana Lai Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jennifer Shi Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, MA, USA PubMed articlesGoogle scholar articles
  • Jeffrey Chan VA Boston Healthcare System, Center for Healthcare Organization and Implementation Research (CHOIR), Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jennifer S Lutz Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Robert W Dubois National Pharmaceutical Council, Washington, District of Columbia, USA PubMed articlesGoogle scholar articles
  • Richard L Kravitz Department of Internal Medicine, University of California, Davis, San Francisco, California, USA PubMed articlesGoogle scholar articles
  • David M Kent Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr David M Kent; dkent1{at}tuftsmedicalcenter.org
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Citation

Raman G, Balk EM, Lai L, et al
Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis

Publication history

  • Received May 8, 2017
  • Revised February 22, 2018
  • Accepted April 13, 2018
  • First published May 26, 2018.
Online issue publication 
May 26, 2018

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