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The French prospective multisite registry on sudden unexpected infant death (OMIN): rationale and study protocol
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  • Published on:
    Interventricular vessel of the heart and sudden infant death syndrome

    I read with interest the article of Levieux K et al concerning French prospective multisite registry on sudden unexpected infant death (OMIN): rationale and study protocol (1). In the formation of the fetal muscular part of the interventricular septum (IVS), the expanding ventricles grow and their medial walls approach and fuse, forming the septum. The inside corner between the septum and the right anterior ventricular wall exhibits the deep pits being called interventricular sinuses (ISs). The IS passes through the right IVS formed from the medial wall of the expanding fetal right ventricle (RV). The opening of the interventricular vessel (IV) (kuuselian vessel) is located in the IS between the medial walls of the expanding fetal RV and fetal left ventricle (LV). The IV is not a canal or channel or blood vessel, but a slit between the fibres of the muscle to the outer layer of the left central muscular part of the IVS and runs at an angle of about 90 degrees through the sphincter and the left IVS into the LV. The IV exhibits 2 to 3 oval 2x5 mm openings in the left central muscular part of the IVS surrounded by the interventricular sphincter (ISP). Hypoxia may be the physiological factor to recruit IV of the fetal heart and augment the flow of the oxygenated blood from right to left. The ISP and the IV are feasible to be patent by relaxing and widening of the helical heart at the right atrial filling phase at the end of the fetal diastole. The sinoatrial node initially ac...

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    Conflict of Interest:
    None declared.