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Obesity and eating disorders in integrative prevention programmes for adolescents: protocol for a systematic review and meta-analysis
  1. Ana Carolina Barco Leme1,
  2. Debbe Thompson1,
  3. Karin Louise Lenz Dunker2,
  4. Theresa Nicklas1,
  5. Sonia Tucunduva Philippi3,
  6. Tabbetha Lopez4,
  7. Lydi-Anne Vézina-Im1,
  8. Tom Baranowski1
  1. 1 Children’s Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA
  2. 2 Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil
  3. 3 School of Public Health, University of São Paulo, São Paulo, Brazil
  4. 4 Department of Health and Human Performance, College of Liberal Arts and Social Sciences, University of Houston, Houston, Texas, USA
  1. Correspondence to Dr Ana Carolina Barco Leme; acarol.leme{at}


Introduction Obesity and eating disorders are public health problems that have lifelong financial and personal costs and common risk factors, for example, body dissatisfaction, weight teasing and disordered eating. Obesity prevention interventions might lead to the development of an eating disorder since focusing on weight may contribute to excessive concern with diet and weight. Therefore, the proposed research will assess whether integrating obesity and eating disorder prevention procedures (‘integrated approach’) do better than single approach interventions in preventing obesity among adolescents, and if integrated approaches influence weight-related outcomes.

Methods and analysis Integrated obesity and eating disorder prevention interventions will be identified. Randomised controlled trials and quasi-experimental trials reporting data on adolescents ranging from 10 to 19 years of age from both sexes will be included. Outcomes of interest include body composition, unhealthy weight control behaviours and body satisfaction measurements. MEDLINE/PubMed, PsycINFO, Web of Science and SciELO will be searched. Data will be extracted independently by two reviewers using a standardised data extraction form. Trial quality will be assessed using the Cochrane Collaboration criteria. The effects of integrated versus single approach intervention studies will be compared using systematic review procedures. If an adequate number of studies report data on integrated interventions among similar populations (k>5), a meta-analysis with random effects will be conducted. Sensitivity analyses and meta-regression will be performed only if between-study heterogeneity is high (I2 ≥75%).

Ethics and dissemination Ethics approval will not be required as this is a systematic review of published studies. The findings will be disseminated through conference presentations and peer-reviewed journals.

  • adolescent
  • obesity prevention
  • eating disorders
  • systematic review
  • disordered eating

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See:

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  • Contributors ACBL, the guarantor of the protocol, drafted the protocol and registered it in PROSPERO. TB reviewed and commented on the protocol in PROSPERO. ACBL, DT, KLLD, TN, STP, TL, L-AV-I and TB all reviewed and commented on this protocol.

  • Funding This work is a publication of the USDA (USDA/ARS - UNITED STATES DEPARTMENT OF AGRICULTURE/AGRICULTURE RESEARCH SERVICE)) Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine (Houston, Texas) and has had been funded, in part, with federal funds from the USDA/ARS under Cooperative Agreement Number 58-6250-6001. ACBL received a postdoctoral fellowship from the State of São Paulo, Brazil (FAPESP - FUNDANÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - process nº 2016/ 21144-9).

  • Competing interests None declared.

  • Patient consent Not required.

  • Ethics approval Ethics approval will not be required as this is a protocol for systematic review and meta-analysis. This systematic review and meta-analysis will be published in a peer-reviewed journal which will be disseminated electronically and in print.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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