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Glycaemic control in type 2 diabetes patients and its predictors: a retrospective database study at a tertiary care diabetes centre in Ningbo, China
  1. Jialin Li1,
  2. Kaushik Chattopadhyay2,
  3. Miao Xu1,
  4. Yanshu Chen1,
  5. Fangfang Hu1,
  6. Jianping Chu1,
  7. Li Li1
  1. 1 Department of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, China
  2. 2 Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK
  1. Correspondence to Dr Li Li; lilyningbo{at}163.com

Abstract

Objectives The objectives of the study were to assess glycaemic control in patients with type 2 diabetes (T2DM) at a tertiary care diabetes centre in Ningbo, China and to determine factors that independently predict their glycaemic control.

Design Retrospective cross-sectional study using an existing database, the Diabetes Information Management System.

Setting Tertiary care diabetes centre in Ningbo, China.

Participants The study included adult patients with T2DM, registered and received treatment at the diabetes centre for at least six consecutive months. The study inclusion criteria were satisfied by 1387 patients, from 1 July 2012 to 30 June 2017.

Primary outcome measure Glycaemic control (poor was defined as glycated haemoglobin (HbA1c)>=7% or fasting blood glucose (FBG)>7.0 mmol/L).

Results In terms of HbA1c and FBG, the 5-year period prevalence of poor glycaemic control was 50.3% and 57.3%, respectively. In terms of HbA1c and FBG, the odds of poor glycaemic control increased with the duration of T2DM (>1 to 2 years: OR 1.84, 95% CI 1.06 to 3.19; >2 to 4 years: 3.32, 1.88 to 5.85 and >4 years: 5.98, 4.09 to 8.75 and >1 to 2 years: 2.10, 1.22 to 3.62; >2 to 4 years: 2.48, 1.42 to 4.34 and >4 years: 3.34, 2.32 to 4.80) and were higher in patients residing in rural areas (1.68, 1.24 to 2.28 and 1.42, 1.06 to 1.91), with hyperlipidaemia (1.57, 1.12 to 2.19 and 1.68, 1.21 to 2.33), on diet, physical activity and oral hypoglycaemic drug (OHD) as part of their T2DM therapeutic regimen (1.80, 1.01 to 3.23 and 2.40, 1.36 to 4.26) and on diet, physical activity, OHD and insulin (2.47, 1.38 to 4.41 and 2.78, 1.58 to 4.92), respectively.

Conclusions More than half of patients with T2DM at the diabetes centre in Ningbo, China have poor glycaemic control, and the predictors of glycaemic control were identified. The study findings could be taken into consideration in future interventional studies aimed at improving glycaemic control in these patients.

  • type 2 diabetes
  • poor glycaemic control
  • China

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Footnotes

  • JL and KC are co-first authors

  • Contributors JL and KC designed the study, analysed the data and wrote the first draft of the manuscript. JL, KC, MX, YC, FH, JC and LL revised it critically for important intellectual content and approved the final version.

  • Funding The study was supported by the Natural Science Foundation of Ningbo Municipality (CN) (Grant No. 2016A610169).

  • Competing interests None declared.

  • Patient consent Detail has been removed from this case description/these case descriptions to ensure anonymity. The editors and reviewers have seen the detailed information available and are satisfied that the information backs up the case the authors are making.

  • Ethics approval The study was ethically approved by the Research Ethics Committee at the Ningbo First Hospital, China.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement The dataset will be available upon request unless there are legal or ethical reasons for not doing so.

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