Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis

Areti Angeliki Veroniki; Patricia Rios; Elise Cogo; Sharon E Straus; Yaron Finkelstein; Ryan Kealey; Emily Reynen; Charlene Soobiah; Kednapa Thavorn; Brian Hutton; Brenda R Hemmelgarn; Fatemeh Yazdi; Jennifer D'Souza; Heather MacDonald; Andrea C Tricco

doi:10.1136/bmjopen-2017-017248

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Neurology

Research

Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis

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Areti Angeliki Veroniki Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Patricia Rios Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Elise Cogo Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Sharon E Straus Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada Department of Medicine, University of Toronto, 27 King’s College Circle, Toronto, Canada PubMed articles Google scholar articles
Yaron Finkelstein The Hospital for Sick Children,555 University Avenue, Toronto, Canada Department of Paediatrics, University of Toronto, Toronto, Canada Department of Pharmacology and Toxicology, University of Toronto, Medical Sciences Building, Toronto, Canada PubMed articles Google scholar articles
Ryan Kealey Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Emily Reynen Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Charlene Soobiah Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada Institute for Health Policy Management & Evaluation,University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Kednapa Thavorn School of Epidemiology,Public Health and Preventive Medicine, University of Ottawa, Ottawa, Canada Clinical Epidemiology Program,Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Canada Institute of Clinical and Evaluative Sciences (ICES uOttawa), Ottawa, Canada PubMed articles Google scholar articles
Brian Hutton School of Epidemiology,Public Health and Preventive Medicine, University of Ottawa, Ottawa, Canada Ottawa Hospital Research Institute,Center for Practice Changing Research, Ottawa, Canada PubMed articles Google scholar articles
Brenda R Hemmelgarn Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Canada PubMed articles Google scholar articles
Fatemeh Yazdi Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Jennifer D'Souza Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Heather MacDonald Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada PubMed articles Google scholar articles
Andrea C Tricco Li Ka Shing Knowledge Institute,St. Michael’s Hospital, Toronto, Canada Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada PubMed articles Google scholar articles

Correspondence to Dr Andrea C Tricco; triccoa{at}smh.ca

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Veroniki AA, Rios P, Cogo E, et al

Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis

BMJ Open 2017;7:e017248. doi: 10.1136/bmjopen-2017-017248

Publication history

Received April 10, 2017
Revised June 1, 2017
Accepted June 2, 2017
First published July 20, 2017.

Online issue publication

July 20, 2017

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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