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A cross-sectional study on prevalence of chronic obstructive pulmonary disease (COPD) in India: rationale and methods
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    Newly developed spirometry prediction models for Indian adults

    I read the article written by Rajkumar et al. [1] with great interest and appreciate the efforts taken by the investigators to screen the prevalence of COPD in different age groups in India. However, there are two aspects on which I would like to make some comments. The authors have stated “Globally COPD was the fourth leading cause of death (5.1%) in 2004 and is projected to occupy the third position (8.6%) in 2030”, I assume that the statistics are quite overestimated. Mathers and Loncar (2006) [2], provided a more comprehensive picture about the projected scenario of COPD globally and they concluded that COPD is at present the 5th leading cause of mortality and morbidity globally and is likely to step up to 4th position by 2030 with an increment of 160%. I think that the authors need to consider the fact. Secondly, the authors might have missed that recently, Desai and colleagues (2016) have published spirometry prediction equations for Indian adults residing in the western parts of India [3]. The equations have successfully overcome a long-awaited aspiration for standard prediction models in Indian perspective and could be used as Indian standard. Most of the existing prediction models such as the global lung function equations developed by Quanjer et al. (2012) [4] which were developed for Europeans either under-diagnose or over-diagnose the disease, hence I think the newly published models would serve the purpose.

    1. Rajkumar P, Pattabi K, Va...

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    Conflict of Interest:
    The author personally knows Drs. Bill Brashier and Arvind Bhome and has closely worked with them. The Author also declares personal fees from the Current Respiratory Medicine Reviews, the Lancet Respiratory Medicine and the European Respiratory Society outside the present submission.