Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU)

Gareth A L Jones; Padmanabhan Ramnarayan; Sainath Raman; David Inwald; Michael P W Grocott; Simon Eaton; Samiran Ray; Michael J Griksaitis; John Pappachan; Daisy Wiley; Paul R Mouncey; Jerome Wulff; David A Harrison; Kathryn M Rowan; Mark J Peters

doi:10.1136/bmjopen-2017-019253

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Paediatrics

Protocol

Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU)

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Gareth A L Jones Respiratory Critical Care and Anaesthesia Unit, UCL Great Ormond Street Institute of Child Health, London, UK Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, UK PubMed articles Google scholar articles
Padmanabhan Ramnarayan Children’s Acute Transport Service, Great Ormond Street Hospital, London, UK Paediatric Intensive Care Unit, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK PubMed articles Google scholar articles
Sainath Raman Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, UK PubMed articles Google scholar articles
David Inwald Paediatric Intensive Care Unit, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK PubMed articles Google scholar articles
Michael P W Grocott Critical Care Research Group, Southampton NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust/University of Southampton, Southampton, UK PubMed articles Google scholar articles
Simon Eaton Stem Cells and Regenerative Medicine Section, UCL Great Ormond Street Institute of Child Health, London, UK PubMed articles Google scholar articles
Samiran Ray Respiratory Critical Care and Anaesthesia Unit, UCL Great Ormond Street Institute of Child Health, London, UK Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, UK PubMed articles Google scholar articles
Michael J Griksaitis Paediatric Intensive Care Unit, Southampton General Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK PubMed articles Google scholar articles
John Pappachan Paediatric Intensive Care Unit, Southampton General Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, UK PubMed articles Google scholar articles
Daisy Wiley Clinical Trials Unit, Intensive Care National Audit & Research Centre, 24 High Holborn, London, UK PubMed articles Google scholar articles
Paul R Mouncey Clinical Trials Unit, Intensive Care National Audit & Research Centre, 24 High Holborn, London, UK PubMed articles Google scholar articles
Jerome Wulff Clinical Trials Unit, Intensive Care National Audit & Research Centre, 24 High Holborn, London, UK PubMed articles Google scholar articles
David A Harrison Clinical Trials Unit, Intensive Care National Audit & Research Centre, 24 High Holborn, London, UK PubMed articles Google scholar articles
Kathryn M Rowan Clinical Trials Unit, Intensive Care National Audit & Research Centre, 24 High Holborn, London, UK PubMed articles Google scholar articles
Mark J Peters Respiratory Critical Care and Anaesthesia Unit, UCL Great Ormond Street Institute of Child Health, London, UK Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, UK PubMed articles Google scholar articles
On behalf of the Oxy-PICU Investigators for thePaediatric Intensive Care Society-Study Group (PICS-SG)
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Correspondence to Professor Mark J Peters; mark.peters{at}ucl.ac.uk

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Jones GAL, Ramnarayan P, Raman S On behalf of the Oxy-PICU Investigators for thePaediatric Intensive Care Society-Study Group (PICS-SG), et al

Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU)

BMJ Open 2017;7:e019253. doi: 10.1136/bmjopen-2017-019253

Publication history

Received August 21, 2017
Accepted August 23, 2017
First published December 14, 2017.

Online issue publication

January 10, 2022

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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