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Rehabilitation medicine
Protocol
Impairments, activity limitations and participation restrictions experienced in the first year following a critical illness: protocol for a systematic review
  1. Patricia J Ohtake1,
  2. Jacqueline Coffey Scott2,
  3. Rana S Hinman3,
  4. Alan Chong Lee4,
  5. James M Smith5
  1. 1Department of Rehabilitation Science, University at Buffalo, Buffalo, New York, USA
  2. 2Montante Family Library, D'Youville College, Buffalo, New York, USA
  3. 3Department of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia
  4. 4Department of Physical Therapy, Mount Saint Mary's University, Los Angeles, California, USA
  5. 5Physical Therapy Department, Utica College, Utica, New York, USA
  1. Correspondence to Dr Patricia J Ohtake; ohtake{at}buffalo.edu

Abstract

Introduction Critical illness requiring intensive care unit (ICU) management is a life-altering event with ∼25% of ICU survivors experiencing persistent reductions in physical functioning, impairments in mental health, cognitive dysfunction and decreased quality of life. This constellation of problems is known as ‘postintensive care syndrome’ (PICS) and may persist for months and/or years. The purpose of this systematic review is to identify the scope and magnitude of physical problems associated with PICS during the first year after discharge from ICU, using the International Classification of Functioning, Disability and Health framework to elucidate the impairments of body functions and structures, activity limitations and participation restrictions.

Methods and analysis Medline (Ovid), Cochrane Database of Systematic Reviews (Ovid), Cochrane Central Register of Controlled Trials (Ovid), PubMed, CINAHL (EBSCO), Web of Science and EMBASE will be systematically searched for observational studies reporting the physical impairments of body functions and structures, activity limitations and participation restrictions associated with PICS. Two reviewers will assess the articles for eligibility according to prespecified selection criteria, after which an independent reviewer will perform data extraction which will be validated by a second independent reviewer. Quality appraisal will be performed by two independent reviewers. Outcomes of the included studies will be summarised in tables and in narrative format and meta-analyses will be conducted where appropriate.

Ethics and dissemination Formal ethical approval is not required as no primary data is collected. This systematic review will identify the scope and magnitude of physical problems associated with PICS during the first year after discharge from ICU and will be disseminated through a peer-reviewed publication and at conference meetings, to inform practice and future research on the physical problems associated with PICS.

Trial registration number CRD42015023520.

  • post-intensive care syndrome
  • ICF
  • ICU Survivor
  • physical functioning
  • activities of daily living

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bmjopen-2016-013847

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    Footnotes

    • Twitter Follow Alan Lee @alanleeDPT

    • Contributors PJO is the guarantor. PJO, JCS, RSH, ACL and JMS conceived the idea, planned and designed the study protocol. RSH provided expertise for the data extraction, reporting and statistical analyses. JCS provided the search strategy. JMS wrote the first draft and PJO developed the final version after critical feedback from all authors. All authors have approved the final version of the manuscript.

    • Funding This work was supported by grants from the American Physical Therapy Association and the Academy of Acute Care Physical Therapy.

    • Disclaimer The sponsors had no part in the development of this protocol.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.