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Forty years of shunt surgery at Rigshospitalet, Denmark: a retrospective study comparing past and present rates and causes of revision and infection
  1. Philip Kofoed Månsson,
  2. Sofia Johansson,
  3. Morten Ziebell,
  4. Marianne Juhler
  1. Department of Neurosurgery, Copenhagen University Hospital, Copenhagen, Denmark
  1. Correspondence to Philip Kofoed Månsson; phmaans{at}hotmail.com

Abstract

Objective The objective of this study is to review our experience of shunt surgery by investigating 40 years of development in terms of rates of revision and infection, shunt survival and risk factors.

Design and participants Medical records and operative reports were reviewed retrospectively for all patients who underwent primary shunt surgery at our department in the years 2010 to 2012. All results were compared with a previous study from our department. A mixed population consisting of 434 patients was included. Adults (≥15 years) accounted for 89.9% of all patients and the mean follow-up time was 1.71 years.

Results Overall, 42.6% had a revision of which 65.4% fell within 6 months postoperatively. Low age, high-risk diagnoses and less severe brain injury were associated with a higher risk of revision. One and 5-year shunt survival probabilities were 66.2% (61.5–70.9) and 48.0% (41.1–54.9). Within 4 weeks postoperatively, 3.2% had an infection and overall infection rate was 5.5%. Short duration of surgery and the use of antibiotic prophylaxis were associated with a lower risk of infection. The most frequent causes of revision were valve defects (18.4%) and proximal defects or obstructions (15.7%). Compared to the previous study, no convincing improvement was found with regard to the revision rate (42.6% vs 48.3%, p 0.060) or overall infection rate (5.5% vs 7.4%, p 0.261).

Conclusions Regardless of changes in patient demographics, techniques and equipment, risk of revision and infection still constitutes a major challenge in shunt surgery. The absence of convincing improvements calls for more studies concerning strategies to reduce complications.

  • NEUROSURGERY
  • Hydrocephalus

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Footnotes

  • Contributors SJ made a preliminary smaller scale study and thus contributed significantly to the concept of this study. Data collecting was performed by PKM under the supervision of MZ and MJ. The statistical analysis was performed by PKM and interpreted in corporation with MZ and MJ. All authors have critically revised the manuscript.

  • Funding This work was supported by The Lundbeck Foundation in the form of a scholarship for a total of 140 000 DKK to the first author. The sponsor had no role in the design or conduct of this research.

  • Competing interests All authors have completed the ICMJE uniform disclosure form at http://www.icmje.org/coi_disclosure.pdf and declare: PKM received financial support from The Lundbeck Foundation.

  • Ethics approval This study was approved by the Danish Health and Medicines Authority with prior permission from the Danish Data Protecting Agency for the handling of personal data.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.