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Intensive care
Protocol
Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION)

Authors

  • Parind B Patel Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Stephen J Brett Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • David O'Callaghan Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK PubMed articlesGoogle scholar articles
  • Aisha Anjum Imperial Clinical Trials Unit, Faculty of Medicine, School of Public Health, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Mary Cross Imperial Clinical Trials Unit, Faculty of Medicine, School of Public Health, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Jane Warwick Warwick Clinical Trials Unit, University of Warwick, Coventry, UK PubMed articlesGoogle scholar articles
  • Anthony C Gordon Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Parind B Patel; p.patel{at}imperial.ac.uk
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Citation

Patel PB, Brett SJ, O'Callaghan D, et al
Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION)
BMJ Open 2016;6:e011750. doi: 10.1136/bmjopen-2016-011750

Publication history

  • Received March 2, 2016
  • Revised May 17, 2016
  • Accepted May 25, 2016
  • First published July 13, 2016.
Online issue publication 
October 25, 2017
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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/