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A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease
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  • Published on:
    Iron and COPD: discretion - yes; inaction - no
    • Peter A. Robbins, Professor of Physiology and Head of Department
    • Other Contributors:
      • Annabel H. Nickol, Matthew C. Frise

    We thank Ghio for his interest in our work (1) but are concerned by his suggestion that we are advocating the use of iron as a treatment for COPD. We stated that intravenous iron should be explored as a novel therapeutic option in the condition and we stand by this conclusion. We agree with Ghio that, "Iron metabolism is recognised to participate in the pathogenesis of cancer", but take the view that it is overly simplist...

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    Conflict of Interest:
    None declared.
  • Published on:
    Provision of iron to COPD patients

    Nickol et al. presents an interesting study examining the prevalence of iron deficiency in chronic obstructive pulmonary disease (COPD) and its associations with clinical phenotypes.1 Iron deficiency was observed in 18% of COPD patients and 5% of controls. Extrapolating from other chronic diseases, Nickol et al. suggests that intravenous iron therapy should be explored as a novel therapeutic option in COPD. Prior invest...

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    Conflict of Interest:
    None declared.