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The present study shows an increase in the prevalence of prediabetes
in England since 2003 till 2011. The population based study has strengths
in terms of having an appropriate sampling method, with blood samples for
glycated haemoglobin level estimation for diagnosis of pre diabetes state.
However, some factors need to be considered while analyzing the results.
Firstly, the reported hypertension in the study co...
Firstly, the reported hypertension in the study could be an
underestimate since a large number of hypertensives are undetected. The
present report may also does not indicate about the relationship before or
after onset of the pre diabetes state. Hence, the presence of hypertension
as a risk may not absolutely true.
Secondly, the odds ratio for social deprivation does show a
statistically increase risk in second and fourth quintile only, not for
3rd and 5th quintiles. Hence, the generalized interpretation of risk of
pre-diabetes with increasing social deprivation is not true.
Thirdly, it is surprising that pre-diabetes is prevalent even in
those with BMI less than 25 Kg/m2. It indirectly shows that factors other
than obesity might have played a role in the onset of pre diabetes among
the study population.
Fourthly, generalization about South Asians as a proxy may not give
true picture about the actual prevalence among Sout Asians since there are
wide variations even among them.
Lastly, as mentioned by the authors to some extent, other potential
risk factors have not been studied. Hence, factors such as lifestyle,
diet, sedentary work, family history,stress have not been studied and the
potential risk factors in this study are not fully indicated.