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Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: study protocol for an observational study
  1. Ulf S Nerland1,
  2. Asgeir S Jakola1,2,3,
  3. Ole Solheim1,2,3,
  4. Clemens Weber1,
  5. Vidar Rao1,4,
  6. Greger Lønne4,5,
  7. Tore K Solberg6,7,
  8. Øyvind Salvesen8,
  9. Sven M Carlsen8,9,
  10. Øystein P Nygaard1,4,10,
  11. Sasha Gulati1,11
  1. 1Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway
  2. 2MI Lab, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
  3. 3National Centre of Competence in Ultrasound and Image-Guided Surgery, Trondheim, Norway
  4. 4Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
  5. 5Department of Orthopedics, Sykehuset Innlandet, Lillehammer, Norway
  6. 6Department of Neurosurgery, University Hospital of Northern Norway (UNN), Tromsø, Norway
  7. 7The Norwegian National Registry for Spine Surgery, University Hospital of Northern Norway (UNN), Tromsø, Norway
  8. 8Unit for Applied Clinical Research, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
  9. 9Department of Endocrinology, St. Olavs University Hospital, Trondheim, Norway
  10. 10National Centre for Spinal Disorders, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
  11. 11Norwegian Centre of Competence in Deep Brain Stimulation for Movement Disorders, St. Olavs University Hospital, Trondheim, Norway
  1. Correspondence to Dr Sasha Gulati; sashagulati{at}hotmail.com

Abstract

Introduction This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal stenosis is the most frequent indication for spinal surgery in the elderly, and as the oldest segment of the population continues to grow its prevalence is likely to increase. However, data on surgical outcomes are limited. Open or wide decompressive laminectomy, often combined with medial facetectomy and foraminotomy, was formerly the standard treatment. In recent years a growing tendency towards less invasive decompressive procedures has emerged. At present, many spine surgeons perform microdecompression for central lumbar spinal stenosis.

Methods and analysis Prospectively registered treatment and outcome data are obtained from the Norwegian Registry for Spine Surgery. The primary outcome measure is change in Oswestry disability index between baseline and 12-month follow-up. Secondary outcome measures are changes in health-related quality of life measured by the Euro-Qol-5D between baseline and 12-month follow-up, perioperative complications, and duration of surgical procedures and length of hospital stay.

Ethics and dissemination The study has been evaluated and approved by the regional committee for medical research in central Norway and all participants provided written informed consent. The findings of this study will be disseminated through peer-reviewed publications.

Trial registration number Clinicaltrials.gov (NCT02006901).

  • Neurosurgery

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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