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Prevalence and trend of dyslipidaemia from 1996 to 2006 among normal and overweight adolescents in Taiwan
  1. Philip Kuo1,
  2. Jhu-Ting Syu2,
  3. Isabel Lin Tzou3,
  4. Pi-Yun Chen4,
  5. Hsiu-Yueh Su5,
  6. Nain-Feng Chu6,7,8
  1. 1University of Illinois at Chicago, Chicago, Illinois, USA
  2. 2National Defense Medical Center, Taipei, Taiwan
  3. 3Keck School of Medicine of University of Southern California, Los Angeles, California, USA
  4. 4National Taipei University of Education, Taipei, Taiwan
  5. 5Department of Dietetics, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan
  6. 6Tai-tung Hospital, Ministry of Health and Welfare, Taitung, Taiwan
  7. 7School of Public Health, National Defense Medical Center, Taipei, Taiwan
  8. 8National Defense Medical Center, School of Public Health, Taipei, Taiwan
  1. Correspondence to Professor Nain-Feng Chu; chuepi{at}


Objectives To evaluate the trend of dyslipidaemia from 1996 to 2006 and examine its relationship with weight status among adolescents in Taiwan.

Design 2 cross-sectional surveys were conducted in 1996 and 2006.

Setting The junior high schools in Taipei.

Participants After multistage sampling, total of 1500 and 1283 junior high school students were chosen in 1996 and 2006. After excluding missing data, a total of 1353 (676 boys and 677 girls) and 1203 (585 boys and 618 girls) children were included in the final analyses in 1996 and 2006.

Outcome measures Anthropometric measures as body height and weight were measured, and body mass index (BMI) was calculated. Blood lipid profiles as total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol were measured.

Results From 1996 to 2006, the prevalence of dyslipidaemia and hypercholesterolaemia significantly increased from 13% (95% CI 11.3% to 15.0%) to 22.3% (95% CI 20.0% to 24.7%) and 6.2% (95% CI 5.0% to 7.6%) to 13.8% (95% CI 11.9% to 15.9%), respectively. The prevalence of hypertriglyceridaemia and low HDL-C dyslipidaemia increased from 3% (95% CI 1.8% to 4.5%) to 4.3% (95% CI 2.8% to 6.2%) and 6.5% (95% CI 4.8% to 8.6%) to 11.6% (95% CI 9.1% to 14.5%), with significance seen only in boys. When compared with normal weight participants, overweight boys and girls faced a 2-fold and 1.6-fold increased risk of dyslipidaemia, respectively, in the 2006 study. The increased risk of low HDL-C dyslipidaemia for overweight participants was 2.6-fold and 7.2-fold in boys and girls, respectively. In 2006, each unit increment of BMI was associated with 28%, 13% and 13% risk of hypertriglyceridaemia, low HDL-C and dyslipidaemia for boys, and 25% risk of low HDL-C dyslipidaemia in girls.

Conclusions The prevalence of dyslipidaemia had increased significantly for boys and girls in normal weight and overweight adolescents. Early screening of dyslipidaemia and weight intervention programmes in adolescents will be the key to prevent dyslipidaemia and cardiovascular-related comorbidities.

  • Public Health
  • Basic Sciences

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