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Opportunistic pathology-based screening for diabetes
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  • Published on:
    Limitation of the study
    • Disha Patel, Medical Graduate (doctor) GCS Medical College
    • Other Contributors:
      • Harika Dadigiri, Medical Graduate (doctor)
      • Hriday Shah, Medical Graduate (doctor)

    there are several limitations that should be considered:

    Sampling Bias: The study relies on blood samples collected for unrelated tests, which may introduce a sampling bias. Patients who undergo routine testing may differ from those who do not, potentially affecting the generalizability of the findings to the broader population.

    Cross-Sectional Design: The study design is cross-sectional, meaning it captures data at a single point in time. This limits the ability to establish causation or assess changes over time. Longitudinal studies would provide more robust evidence of the effectiveness of opportunistic screening.

    Exclusion Criteria: The study excludes samples from patients with a previous diagnosis of diabetes or those who underwent diabetes screening in the past 12 months. However, the accuracy of this exclusion depends on the completeness and accuracy of medical records, which might not capture all instances of diabetes diagnoses.

    Age Discrepancies: The study finds age-related differences in HbA1c levels but adjusts for these differences. However, age alone may not capture the complexity of diabetes risk factors. Other factors such as lifestyle, family history, and comorbidities could contribute to variations in HbA1c levels.

    Limited Generalizability: The study is conducted in a specific Australian setting, and the findings may not be directly applicable to other regions with different demographics, healthcare systems, or diabetes p...

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    Conflict of Interest:
    None declared.