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A mixed methods protocol to investigate medication adherence in patients with rheumatoid arthritis of White British and South Asian origin
  1. Kanta Kumar1,
  2. Karim Raza2,
  3. Peter Nightingale3,
  4. Rob Horne4,
  5. Karen Shaw1,
  6. Sheila Greenfield1,
  7. Paramjit Gill1
  1. 1Primary Care, The School of Health and Population Sciences, University of Birmingham, Birmingham, UK
  2. 2Department of Rheumatology, The School of Immunity and Infection, University of Birmingham, Birmingham, UK
  3. 3Wolfson Building, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
  4. 4Centre for Behavioural Medicine, The School of Pharmacy, University of London, London, UK
  1. Correspondence to Kanta Kumar; k.kumar{at}


Background Low adherence to medicines is an important issue as up to 40% of patients with chronic diseases do not take their medications as prescribed. This leads to suboptimal clinical benefit. In the context of rheumatoid arthritis, there is a dearth of data on adherence to disease-modifying antirheumatic drugs among minority ethnic groups. This study aims to assess the relationship between adherence to medicines and biopsychosocial variables in patients with rheumatoid arthritis of South Asian and White British origin.

Methods/analysis A mixed methods approach will be used, encompassing a cross-sectional survey of 176 patients collecting demographic and clinical data, including information on adherence behaviour collected using a series of questionnaires. This will be followed by indepth qualitative interviews.

Ethics and dissemination This study has been approved by the South Birmingham (10/H1207/89) and Coventry and Warwickshire (12/WM/0041) Research Ethics Committees. The authors will disseminate the findings in peer-reviewed publications.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: and

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