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  • Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study

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Respiratory medicine
Protocol
Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study

Authors

  • Kiki Waeijen-Smit Department of Research and Development, CIRO, Horn, NetherlandsDepartment of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University Medical Centre+, Maastricht, Netherlands PubMed articlesGoogle scholar articles
  • Antonio DiGiandomenico Discovery Microbiome, Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA PubMed articlesGoogle scholar articles
  • Jessica Bonnell Discovery Microbiome, Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA PubMed articlesGoogle scholar articles
  • Kristoffer Ostridge Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, SwedenFaculty of Medicine, University of Southampton, Southampton, UK PubMed articlesGoogle scholar articles
  • Ulf Gehrmann Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden PubMed articlesGoogle scholar articles
  • Bret R Sellman Discovery Microbiome, Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA PubMed articlesGoogle scholar articles
  • Tara Kenny Discovery Microbiome, Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA PubMed articlesGoogle scholar articles
  • Sander van Kuijk Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht Universitair Medisch Centrum+, Maastricht, Netherlands PubMed articlesGoogle scholar articles
  • Daphne Peerlings Department of Research and Development, CIRO, Horn, Netherlands PubMed articlesGoogle scholar articles
  • Martijn A Spruit Department of Research and Development, CIRO, Horn, NetherlandsDepartment of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University Medical Centre+, Maastricht, Netherlands PubMed articlesGoogle scholar articles
  • Sami O Simons Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University Medical Centre+, Maastricht, Netherlands PubMed articlesGoogle scholar articles
  • Sarah Houben-Wilke Department of Research and Development, CIRO, Horn, Netherlands PubMed articlesGoogle scholar articles
  • Frits M E Franssen Department of Research and Development, CIRO, Horn, NetherlandsDepartment of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University Medical Centre+, Maastricht, Netherlands PubMed articlesGoogle scholar articles
  1. Correspondence to Kiki Waeijen-Smit; kikismit{at}ciro-horn.nl
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Citation

Waeijen-Smit K, DiGiandomenico A, Bonnell J, et al
Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study
BMJ Open 2023;13:e068787. doi: 10.1136/bmjopen-2022-068787

Publication history

  • Received September 29, 2022
  • Accepted February 22, 2023
  • First published March 3, 2023.
Online issue publication 
March 03, 2023
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  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.