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344 Prognostic value of on-scene analytic parameters for organ viability in DCD donors
  1. JC Yubero,
  2. AB Sánchez,
  3. CS Rodriguez
  1. SAMUR Protección Civil

Abstract

Background An increasing number of Spanish EMS have started Donation after Circulatory Death (DCD) protocols for not Recovery Of Spontaneous Circulation patients (ROSC) (Type IIa donor in the modified Maastricht Classification, Madrid 2011). The decision to proceed with the donation is taken according to established criteria by the transplant coordination and the organ implantation team.

Method Analytical observational: Population: Patients in DCD attended by an EMS with no ROSC who complies with criteria to be included in the DCD code (2009 – 2020) Exclusion: Missed in the system, non-clinical criteria excluded.

Independent variables: Epidemiological (age, sex) analytical parameters: (pH, lactate, glucose, BE, PCO2, bicarbonate). Variable result: Graft viability. Descriptive analysis: central and quantitative dispersion measures. Qualitative variables percentages. Inferential analysis: Student’s T-distribution for quantitative variable, chi-squared for categorical variables. SPSS V17.

Results 136 deceased donors included.

Age: 45.89 (±9.56). Organs were viable in the 82.35% (112) of the cases. The 90.44% of the patients (123) were male.

Age: 46.7 (SD-8.5) viable, 41.7 (SD-12.6) non-viable, p=0.017

Lactate: 6.93 (SD- 2.82) viable, 5.93 (SD-2.5) non- viable, p= 0.181

COH3: 23.73 (SD-8.8) viable, 22.91 (SD-4.6) non – viable, p= 0.681

pH: 7.11 (SD- 0.16) viable, 7.06 (SD-0.34) non – viable, p=0.374

Glucose: 166.3 (SD- 83.9) viable, 141.3 (SD – 78.5) non – viable, p=0.243

Conclusion The differential tendency towards more pathological values in parameters such as bicarbonate and pH when organs were non–viable for donation could be highly engaging. However, reaching significant statistics data has been unfeasible, most likely to the insufficient number of cases available for study. Consequently, adding more cases and other parameters turns necessary.

Conflict of interest None declared.

Funding None declared.

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