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336 Long-term quality of life of out of hospital cardiac arrest (OHCA) survivors: feasibility of using EQ-5D-3L in an Asian population
  1. X Yang1,
  2. C Kwan1,
  3. P Pek2,
  4. S Lim3,
  5. N Shahidah2,
  6. N Graves2,
  7. FJ Siddiqui2,
  8. N Liu4,
  9. A Ho2,
  10. M Ong2,
  11. PAROSStudy Investigators
  1. 1National University of Singapore, Singapore
  2. 2Prehospital and Emergency Research Centre, Health Services and Systems Research, Duke-National University, Singapore, Department of Emergency Medicine, Singapore General Hospital, Singapore
  3. 3Department of Cardiology, National University Heart Centre, Singapore
  4. 4Health Services and Systems Research, Duke-NUS Medical School, Centre for Quantitative Medicine, Duke-NUS Medical School, Institute of Data Science, National University of Singapore, Singapore, SingHealth AI Health Program, Singapore Health Services, Singapore


Background The purpose of this study was to evaluate the health-related Quality of Life (HRQoL) of OHCA survivors in Singapore using EQ-5D-3L and to assess the factors affecting survey response.

Method Adult OHCA patients aged >/= 18 years between April 2014 to December 2017 who survived to hospital discharge or 30 days were included in a retrospective follow-up study using data obtained from a national registry. EMS-witnessed arrests, those of a drowning or traumatic aetiology, or immediately pronounced dead at scene were excluded. Uncontactable and deceased patients at time of survey were deemed ineligible. The remaining were administered the EQ-5D-3L questionnaire via telephone follow-up at different time points.

Results Of 2727 patients with ROSC, 368 (25%) survived to discharge or were alive at 30 days. At point of survey, 77 (20.9%) had passed away and 38 (10.3%) were uncontactable. Of the remaining 253, 121 (47.8%) refused and interviews were conducted with 132 (52.2% ) patients or proxies. The median follow-up time was 24.5 months (19.2, 33.3)

The mean EQ5D index score was 0.77 (SD 0.44), 86 (65.7%) patients had a full score of 1. The mean EQ5D VAS score was 76.3 (SD17.6). Non-responders tended to be older (60.8 vs 54.9, p<0.003), and had poorer neurological status (CPC 3 or 4) (53.7% vs 35.6%, p<0.001).

Conclusion Majority of the OHCA survivors interviewed had a good quality of life post-OHCA at time of follow-up. However, the study was limited by the low response rate, variable follow-up time and selection bias (responders vs non-responders). For future QoL studies, we recommend that follow-up time be standardised after OHCA. Other measurements of HRQoL should be explored in our population.

Conflict of interest No conflict of interests to declare.

Funding None.

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