Article Text
Abstract
Background The purpose of this study was to evaluate the health-related Quality of Life (HRQoL) of OHCA survivors in Singapore using EQ-5D-3L and to assess the factors affecting survey response.
Method Adult OHCA patients aged >/= 18 years between April 2014 to December 2017 who survived to hospital discharge or 30 days were included in a retrospective follow-up study using data obtained from a national registry. EMS-witnessed arrests, those of a drowning or traumatic aetiology, or immediately pronounced dead at scene were excluded. Uncontactable and deceased patients at time of survey were deemed ineligible. The remaining were administered the EQ-5D-3L questionnaire via telephone follow-up at different time points.
Results Of 2727 patients with ROSC, 368 (25%) survived to discharge or were alive at 30 days. At point of survey, 77 (20.9%) had passed away and 38 (10.3%) were uncontactable. Of the remaining 253, 121 (47.8%) refused and interviews were conducted with 132 (52.2% ) patients or proxies. The median follow-up time was 24.5 months (19.2, 33.3)
The mean EQ5D index score was 0.77 (SD 0.44), 86 (65.7%) patients had a full score of 1. The mean EQ5D VAS score was 76.3 (SD17.6). Non-responders tended to be older (60.8 vs 54.9, p<0.003), and had poorer neurological status (CPC 3 or 4) (53.7% vs 35.6%, p<0.001).
Conclusion Majority of the OHCA survivors interviewed had a good quality of life post-OHCA at time of follow-up. However, the study was limited by the low response rate, variable follow-up time and selection bias (responders vs non-responders). For future QoL studies, we recommend that follow-up time be standardised after OHCA. Other measurements of HRQoL should be explored in our population.
Conflict of interest No conflict of interests to declare.
Funding None.
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ .