You are here

  • Home
  • Archive
  • Volume 12, Issue 10
  • Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol

Article info

Article menu
Intensive care
Protocol
Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol

Authors

  • Alexis F Turgeon Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Dean A Fergusson Clinical Epidemiology, Ottawa Hospital Research Institute, Ottawa, Ontario, CanadaDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Lucy Clayton Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaCentre de Recherche du CHU Sainte-Justine, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Marie-Pier Patton Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Ryan Zarychanski Department of Internal Medicine, Section of Hematology/Oncology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, CanadaCancerCare Manitoba Research Institute, CancerCare Manitoba, Winnipeg, Manitoba, Canada PubMed articlesGoogle scholar articles
  • Shane English Clinical Epidemiology, Ottawa Hospital Research Institute, Ottawa, Ontario, CanadaDepartment of Medicine, University of Ottawa, Ottawa, Ontario, CanadaDepartment of Critical Care, The Ottawa Hospital, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Annemarie Docherty Centre for Medical Informatics, Usher Institute, The University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Timothy Walsh Centre for Medical Informatics, Usher Institute, The University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Donald Griesdale Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaCenter for Clinical Epidemiology & Evaluation, Vancouver General Hospital, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada PubMed articlesGoogle scholar articles
  • Andreas H Kramer Department of Critical Care Medicine, Foothills Medical Center, University of Calgary, Calgary, Alberta, Canada PubMed articlesGoogle scholar articles
  • Damon Scales Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Karen E. A. Burns Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, CanadaLi Ka Shing Knowledge Institute, Unity Health Toronto-St. Michael’s Hospital, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • John Gordon Boyd Department of Medicine, Division of Neurology, Queen's University, Kingston, Ontario, CanadaDepartment of Medicine, Division of Critical Care Medicine, Queen's University, Kingston, Ontario, Canada PubMed articlesGoogle scholar articles
  • John C Marshall Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, CanadaLi Ka Shing Knowledge Institute, Unity Health Toronto-St. Michael’s Hospital, Toronto, Ontario, CanadaDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Demetrios J Kutsogiannis Department of Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada PubMed articlesGoogle scholar articles
  • Ian Ball Department of Medicine, Western University, London, Ontario, CanadaDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada PubMed articlesGoogle scholar articles
  • Paul C Hébert Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Francois Lamontagne Department of Medicine, Université de Sherbrooke, Sherbrooke, Québec, CanadaCentre de Recherche du CHU de Sherbrooke, Centre Intégré Universitaire de Santé et de Services Sociaux de l’Estrie–Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec, Canada PubMed articlesGoogle scholar articles
  • Olivier Costerousse Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Maude St-Onge Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Québec City, Québec, CanadaDepartment of Family and Emergency Medicine, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Paule Lessard Bonaventure Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Surgery, Division of Neurosurgery, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Lynne Moore Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Social and Preventive Medicine, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Xavier Neveu Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Andrea Rigamonti Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Anesthesiology, St. Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Kosar Khwaja Department of Critical Care Medicine, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Robert S Green Departments of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, CanadaDepartment of Critical Care, Dalhousie University, Halifax, Nova Scotia, Canada PubMed articlesGoogle scholar articles
  • Vincent Laroche Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Medicine, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • Alison Fox-Robichaud Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada PubMed articlesGoogle scholar articles
  • Francois Lauzier Population Health and Optimal Practices Research Unit (Trauma— Emergency—Critical Care Medicine), CHU de Québec-Universite Laval Research Center, Québec City, Québec, CanadaDepartment of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Québec City, Québec, CanadaDepartment of Medicine, Université Laval, Québec City, Québec, Canada PubMed articlesGoogle scholar articles
  • for the HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium
    Google scholar articles
  1. Correspondence to Dr Alexis F Turgeon; alexis.turgeon{at}fmed.ulaval.ca
View Full Text

Citation

Turgeon AF, Fergusson DA, Clayton L for the HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium, et al
Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol
BMJ Open 2022;12:e067117. doi: 10.1136/bmjopen-2022-067117

Publication history

  • Received August 2, 2022
  • Accepted September 16, 2022
  • First published October 10, 2022.
Online issue publication 
October 10, 2022
Previous versions
Review history

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.