Article Text

Original research
Training and education of healthcare workers during viral epidemics: a systematic review
  1. Leizl Joy Nayahangan1,
  2. Lars Konge1,2,
  3. Lene Russell1,3,
  4. Steven Andersen1,4,5
  1. 1Copenhagen Academy for Medical Education and Simulation (CAMES), Centre for Human Resouces and Education, The Capital Region of Denmark, Copenhagen, Denmark
  2. 2Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
  3. 3Department of Intensive Care, Rigshospitalet, Copenhagen, Denmark
  4. 4Department of Otorhinolaryngology—Head & Neck Surgery, Rigshospitalet, Copenhagen, Denmark
  5. 5Department of Otolaryngology, Ohio State University, Columbus, Ohio, USA
  1. Correspondence to Leizl Joy Nayahangan; leizl.joy.nayahangan{at}regionh.dk

Abstract

Background It is necessary to train a large number of healthcare workers (HCW) within a limited time to ensure adequate human resources during an epidemic. There remains an urgent need for best practices on development and implementation of training programmes.

Objective To explore published literature in relation to training and education for viral epidemics as well as the effect of these interventions to inform training of HCW.

Data sources Systematic searches in five databases performed between 1 January 2000 and 24 April 2020 for studies reporting on educational interventions in response to major viral epidemics.

Study eligibility criteria All studies on educational interventions developed, implemented and evaluated in response to major global viral outbreaks from 2000 to 2020.

Participants Healthcare workers.

Interventions Educational or training interventions.

Study appraisal and synthesis methods Descriptive information were extracted and synthesised according to content, competency category, educational methodology, educational effects and level of educational outcome. Quality appraisal was performed using a criterion-based checklist.

Results A total of 15 676 records were identified and 46 studies were included. Most studies were motivated by the Ebola virus outbreak with doctors and nurses as primary learners. Traditional didactic methods were commonly used to teach theoretical knowledge. Simulation-based training was used mainly for training of technical skills, such as donning and doffing of personal protective equipment. Evaluation of the interventions consisted mostly of surveys on learner satisfaction and confidence or tests of knowledge and skills. Only three studies investigated transfer to the clinical setting or effect on patient outcomes.

Conclusions and implications of findings The included studies describe important educational experiences from past epidemics with a variety of educational content, design and modes of delivery. High-level educational evidence is limited. Evidence-based and standardised training programmes that are easily adapted locally are recommended in preparation for future outbreaks.

  • COVID-19
  • medical education & training
  • education & training (see medical education & training)

Data availability statement

All data relevant to the study are included in the article or uploaded as supplementary information. An overview of the educational interventional studies included in this systematic review regarding training and education of healthcare workers during viral epidemics including characteristics and general description is uploaded as a supplementary information (Table S1). No additional data available.

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Strengths and limitations of this study

  • Inclusion of educational interventional studies in the last 20 years, providing an overview of currently published training programmes for healthcare workers and evidence of educational impact.

  • Systematic search of five academic databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

  • Final inclusion of 46 studies reporting on educational interventions implemented in response to SARS, Middle East respiratory syndrome, Ebola virus disease and COVID-19.

  • Exclusion of descriptive studies reporting on development of training programmes without evaluation and studies reporting on organisational outcomes with no relevance to training nor evaluation of educational effects.

  • Important educational efforts not described in published form were not included.

Introduction

Global-scale infectious diseases engender threat, vulnerability and risk to health and healthcare capacity as well as the economic and political stature of a nation.1 In the last 20 years, the world has seen several major epidemic outbreaks caused by viral agents—namely SARS in 2003,2 swine influenza (H1N1 influenza virus infection)3 in 2009–2019, Middle East respiratory syndrome (MERS) in 2012,4 and Ebola virus disease (EVD) in 2014–2016.5 Currently, the entire world is facing a pandemic with a COVID-19,6 a new and fast spreading viral agent that can challenged and even overwhelm healthcare delivery and capacity as well as human resources. These viral outbreaks have prompted the need for global communities to swiftly plan, prepare and ensure continuous healthcare functionality, resource availability and skilled manpower to increase surge capacity.7

Healthcare professionals from across different areas were called to help and needed to learn new procedures including correct use of personal protective equipment (PPE)8 and management of critically ill patients on ventilatory support.9 To ensure adequate resources and staffing, it was necessary to quickly train a large number of healthcare workers (HCW) to be on the frontlines. Ideally, training and education in preparation for a new infectious threat should be continuous and planned ahead of time. Specialised training equips HCW with the knowledge and skills to safely provide patient care; to reduce fatalities during an outbreak; and to prevent and control nosocomial infections.10–12

The experiences learnt from previous viral epidemics have helped some countries such as China and Saudi Arabia to deal with and respond to the current COVID-19 pandemic.13 14 However, this is not always the case: some countries that ranked high in the preparedness for pandemics assessed via the Global Health Security Index showed inconsistencies with their actual performance during the current COVID-19 pandemic.15 While there are key capacities that were considered in this performance assessment, the current pandemic has highlighted the need to increase the number of sufficiently trained HCW.16 There remains an urgent need for best practices on development and implementation of training programmes during an epidemic.

In this systematic review, we sought to answer three specific research questions:

  1. What are the educational content and types of competencies being trained in relation to HCW as a result of a major viral epidemic?

  2. How can training be delivered under these conditions?

  3. What are the reported effects of the training interventions?

The overall aim of the study was to provide an overview of the published literature in relation to training and education of HCW during viral epidemics and to explore the educational content of these interventions and the level of competencies being trained. We also sought to present a status on the evidence of effects of these training interventions.

Methods

This systematic review was conducted and reported in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guideline.17

Study eligibility

We considered all studies on educational or training interventions developed, evaluated and/or implemented in response to major global viral outbreaks transmitted via close person-to-person contact from 2000 to 2020: SARS, H1N1, MERS, EVD and COVID-19. Inclusion criteria included studies reporting on development, implementation and evaluation of educational interventions for HCW, while the exclusion criteria were studies that were not in English language, descriptive studies, and those reporting on organisational outcomes with no relevance to training nor any outcome measures to evaluate the effect of training (table 1).

Table 1

Inclusion and exclusion criteria for inclusion in a systematic review on training and education of healthcare workers during viral epidemics

Search strategy

The search strategy was designed to access published literature in health professions education and clinical journals. Five databases were searched from 1 January 2000 to 24 April 2020 (PubMed, Excerpta Medica (EMBASE)/Ovid, Cochrane Library, Web of Science and Directory of Open Access Journals) using the search terms (training OR educat* OR teach*) AND (coronavirus OR SARS OR H1N1 OR MERS OR EBOLA OR COVID-19). See table 2 for full search details.

Table 2

Search strings used in a systematic review on training and education of healthcare workers during viral epidemics

Study selection

The search results were retrieved and imported into the Mendeley software (London, UK). Two authors (LJN and SA) independently reviewed and screened titles and abstracts, and eligible studies were included for full-text screening using Covidence (Veritas Health Innovation, Melbourne, Australia). The same reviewers independently screened the studies for eligibility and final inclusion. Disagreements were resolved with the remaining co-authors.

Data extraction and synthesis

A data extraction form was developed in REDCap (Vanderbilt University, USA) and was piloted with five randomly selected studies. Discrepancies in extraction and analysis by the two reviewers were discussed and the form was revised. The following details were extracted: general study information including study design; viral illness; target learner population and learner level; competency category; educational modality; description of intervention; description of educational outcomes; quality appraisal of the educational intervention in different stages (preparation, intervention and evaluation) based on a structured criterion-based checklist18; and level of educational outcome based on Kirkpatrick’s levels and education evidence.19 Synthesis was aligned with the three research questions. It was decided a priori to forego meta-analyses because of our specific research questions and expected variety of study population, interventions, context and educational outcomes.

Patient and public involvement

There were no patients nor the public that were involved in the design, or conduct, or reporting, or dissemination plans of this systematic review.

Results

Study selection process

Flow chart is provided in figure 1. A total of 15 676 records were identified through the searches. Of these, 10 092 studies remained after removal of duplicates and studies not reported in English. Overall, 304 studies were included for full-text screening, of which 46 studies fulfilled the inclusion criteria (online supplemental table S1).

Figure 1

Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart of the study search and selection process for a systematic review on training and education of healthcare workers during viral epidemics.

Study characteristics

Study characteristics are presented in table 3. A majority of the studies reported on learning interventions developed in response to EVD (n=24, 52%),20–43 eight studies were motivated by SARS (17%),44–51 seven studies by H1N1 influenza (15%),52–58 one study by MERS (2%)59 and three studies were motivated by more than one disease.60–62 Three studies were published in relation to COVID-19.63–65

Table 3

Characteristics of the educational interventional studies included in a systematic review on training and education of healthcare workers during viral epidemics

The majority of the studies used a single-group study design (n=16, 37%) or were educational cohort studies (n=16, 35%). Two were non-randomised trials (4%)36 47 and six studies were randomised controlled trials (13%).21 42 45 50 57 64 Medical doctors and nurses were the targeted learners in most of the studies (n=18 (39%) and n=25 (54%), respectively). Other healthcare professionals included were for example paramedics,20 59 respiratory therapists,38 50 58 pharmacists43 58 61 and midwives.39 42 43 Students in relevant fields were included in some studies.28 29 48 49 55 60 64 65

Educational content and competency category

Theoretical knowledge

Thirty-five studies (76%) reported on development of theoretical courses to educate and inform HCW regarding general principles of epidemic preparedness, disease presentation, surveillance and treatment. Resources for course content could originate from international agencies such as the WHO, from the Centers for Disease Control and Prevention66 or from official guidelines implemented by local health and infectious disease authorities to aid the hospitals.26 Knowledge on infection prevention and control (IPC) including patient care principles and safety practices were central in many of the included studies.23 27 33 36 37 43 47 51 60

Technical skills

In 26 studies (57%), the focus was on technical skills particularly on risk management strategies such as donning and doffing of PPE.20 21 27 28 31 36–38 40 43 52 59 63 64 One study reported that while PPE skills can be mastered in a controlled learning environment, maintaining the integrity of the procedure during critical situations is challenging, as well as measures to reduce risk of self-contamination.20 21 Critical care management skills were also often trained including endotracheal intubation, airway management techniques, manual and mechanical ventilation27 38 60 65; advanced cardiac and airway life support (ACLS/AALS)44 46; and extracorporeal membrane oxygenation (ECMO) management.53 56

‘Non-technical’ skills

Eight (17%) studies described a variety of other skills such as teamwork and cognitive load,21 interpersonal skills, reporting and decision making,49 attitude,39 critical thinking skills,61 concern and confidence.32 Psychological support for HCW was highlighted in three studies that designed educational interventions on psychological first aid42 and resilience.57 62 Another study highlighted the importance of interpersonal skills for screening personnel to manage the high number of potentially anxious patients and visitors.49

Training delivery

Traditional didactics

Thirteen out of forty-six studies (28%) used traditional didactics such as lectures and other adult learning strategies including interactive group and learner-led discussions,52 54 61 case-based learning,29 55 problem-based learning,48 demonstrations/return demonstrations41 49 and role playing.49 54 Most of the studies that aimed to convey theoretical knowledge consisted of brief sessions, that is, less than a day (n=8/13, 62%).41 42 48–51 61 62

E-learning

E-learning has been used to rapidly disseminate information during an epidemic outbreak. One study found that e-learning could be used to significantly increase knowledge on a prelearning and postlearning test as well as retention test.32 Other studies used CD/DVD or USB drives to disseminate course materials for self-learning, as well as audio/video mini lectures35 47 57 60 and specific software for interactive online learning.36 39

Simulation-based training

In 31 studies (67%), simulation-based training (SBT) was an integral part of the training intervention. This ranged from skills stations to practice relevant clinical procedures such as airway management or central venous catheter placement,27 38 63 to the use of high-fidelity and interactive simulation equipment for large scale scenario training.24 27 44 The majority of the studies focused on training of correct use of PPE, while a few studies also used simulation to train interpersonal skills and team training.38 56 58 The duration of SBT was variable across studies, ranging from shorter sessions21 44 64 to multi-day courses.26 33 36 37 43 53

Effects and level of educational outcome

Eight out of forty-six studies (17%) evaluated the learning outcome at Kirkpatrick level 1, that is, the learners’ satisfaction and experience with the training intervention. All these studies concordantly found that learners were satisfied with training regardless of the intervention.24 31 37 44 49 53 60 62

Modification of attitude or perceptions (Kirkpatrick level 2a) were an outcome in five studies (11%). In one of these studies it was reported that the participants felt more confident after the intervention that consisted of 80 hours of lectures and SBT of care and management of the infected patient.27

The majority of the studies (n=29, 63%) reported on modification of knowledge and/or skills (Kirkpatrick level 2b) resulting from the educational intervention. A significant decrease in number of errors in donning and doffing of PPE was demonstrated in one study after a single 1-hour theoretical session combined with three simulation sessions, which were repeated after 72 hours.28 A longer 3-day course of e-learning and SBT regarding safety measures in patient with EVD care reported a significant increase in knowledge scores from pre to post intervention as well as an overall high performance in the simulation scenario on PPE use.36

Only one study reported on behavioural change in the clinic among the participants who correctly used PPE after supplemental SBT as compared with the ones who underwent the standard training (Kirkpatrick level 3).45 Change in organisational practice (Kirkpatrick level 4a) was reported following SBT in IPC, which led to a decrease in infection rate among HCW.23 Two studies included Kirkpatrick level 4b evaluation by demonstrating a benefit to patients or clients directly attributable to the training intervention.23 56 In one of these, decreased mortality rates in ECMO patients was found after implementation of an ECMO training programme (66.7% vs 91.3%, p=0.013).56

Discussion

In this systematic review, we identified 46 studies on training and educational interventions for HCW that were developed and implemented due to an ongoing or a recent major viral epidemic.

Target population and characteristics

Most of the educational interventions were prompted by the urgent need to train HCW, especially in relation to the EVD outbreak, which had the highest case fatality rate at 40.4% compared with SARS (9.6%), MERS (34%), H1N1 (0.02%) and COVID-19 (3.4% as of 3 March 2020).67 EVD training programmes were initiated for all HCW who were deployed to the frontlines mainly focused on IPC procedures and the proper use of PPE. For the other viral diseases, a surge of critically ill patients with respiratory failure has prompted many of the simulation-based interventions to train critical care management skills such as ACLS/AALS and ECMO.44 46 53 56 All these high-risk infections also expose HCW to psychological hazards such as fatigue, occupational burnout and distress, furthermore highlighting that psychological support to maintain the well-being of HCW during a pandemic is imperative, as seen in a number of studies.34 42 62 68

Educational content and competency category

The use of traditional didactic methods to teach theoretical knowledge is common when a large number of learners need to be targeted at the same time. Depending on the learning goals, theoretical knowledge can be efficiently delivered in less than a day, and brief sessions are particularly efficient if modules are spaced (ie, distributed learning) as demonstrated in several of the included studies.28 46 61

The advent of e-learning, including web based and other technology enhanced learning, has opened immense opportunities for flexible dissemination of information notwithstanding time and location.69 This poses an advantage, especially for HCW in remote locations, where learning resources can be accessed in their own time and without potential transmission of infection between the learners. E-learning is dependent on online access, which could be a challenge in rural communities with limited network coverage.35 In light of COVID-19, the WHO Health Emergencies Programme has launched free online training resources, providing HCW and staff access to real-time knowledge on how to detect, prevent and respond to the new coronavirus.70 In medical education, e-learning has been found to have large positive effects and is especially effective when combined with other educational modalities.69

SBT has also been increasingly used as an integral part of medical training with positive effects on knowledge, skills and behaviours.71 72 In the context of a viral outbreak, simulation provides a safe and controlled environment for training of emergency response including teamwork and system readiness. This is corroborated by the included studies on PPE, which found that participants benefitted from repeated training of donning and doffing; of efficiently performing procedures while wearing a constricting PPE; and the use of full-scale scenarios for team-based training.38 44

These three major educational strategies can all be used in combination and integrated in a structured curriculum to achieve an optimised learning experience.73 Several of the included studies achieved this by using e-learning to provide precourse materials, allowing for self-learning prior to course start, then theoretical teaching through lectures and other interactive learning strategies such as group exercises and discussions, and finally practical skills training in a simulated setting.74 Multimodality and extensive training presents a challenge especially for countries with limited resources;75 however, standardised training programmes that are supported by the international communities and the local government bodies seem to help alleviate this.

Training delivery and effects and level of educational outcome

In the included studies, effect of training varied across educational strategies and mode of evaluation. Interestingly, duration of the training intervention did not seem to correlate with the relative effect on the educational outcome: for example, a 3-day workshop on EVD management resulted in an increase of correctly answered questions from a preworkshop median of 7 to a postmedian of 9 (~29% increase)26; whereas a 3-hour training session on EVD awareness demonstrated an improvement in knowledge from the mean baseline score of 3.93 to a mean score of 13.18 after intervention (~235% increase).41 This illustrates that training outcome is very much dependent on the objectives of the training and how it is evaluated. It is also important to be critical in regard to the size of the effects of training reported: a 2-hour session on SARS47 reported a statistically significant increase in knowledge; however, the actual change in test scores from pretraining to posttraining intervention was only 3%, and therefore of limited consequence.

Most of the included studies reported outcomes of the educational intervention at the level of learner satisfaction (level 1), modification of attitude (level 2a) and modification of knowledge and skills (level 2b) without evaluating if the training affected clinical practice. Learner satisfaction and attitude are typically measured using postcourse surveys and changes in knowledge and skills by pretraining and posttraining tests. Unsurprisingly, these will almost always result in high levels of satisfaction, increase in confidence and improvement in knowledge and skills after intervention.76 Further, these outcomes provide little-to-no information on actual performance and translation into improved performance in the clinical environment and/or patient outcomes.76

Implications and perspectives

The current pandemic has highlighted that despite many relevant training interventions already developed, these seem to not have been widely adapted or implemented. There is a need for structured and evidence-based training programmes that are easily replicated and adaptable to local contexts and settings.18 Development of educational interventions should follow a systematic approach such as Kern’s six-step model73: starting with a general needs assessment to identify gaps and learner needs; a targeted needs assessment to align to targeted context; definition of goals and objectives including plans for assessment to ensure that the learning goals are met and that learning outcomes are measured appropriately (ie, knowledge and skills transfer into the clinical environment)77 78; selection of educational modalities, which could include different categories of knowledge, technical skills and ‘non-technical’ skills)73 79; and finally, plans for implementation and evaluation of the training programme.

Training should be optimised and implemented based on learning needs, conditions and resources, allowing for deliberate and distributed practice over time.80 Assessment of the effect of learning interventions plays a critical role and ultimately, provides evidence for improved patient outcomes.73 81 At present, evidence regarding training and education in preparation for a viral epidemic is sparse and not any of the interventions included in this review has followed a structured model for curriculum development nor has undergone rigorous evaluation.

We recommend medical educators to share and publish their actual results or design of educational studies as additional resources in keeping with high standards and to collect evidence for their educational interventions.82 To ensure that key information are gathered and reported, the criterion-based checklist that was used in this study can guide the development and implementation of quality educational interventions. Interestingly, we note that scientific studies spike during or shortly after the onset of the viral epidemic and tend to decline after a few years. With more than 61 000 studies found in PubMed relating to the 5 viral diseases, less than 6% relates to education and training and of these, only 46 were educational interventional studies. This further highlights the need for careful planning and refinement of training interventions also post epidemic, by systematically improving educational approach, study design and outcome measures so that these efforts can prepare the medical community best possibly for the next epidemic. Educational research should not solely be performed during an ongoing viral epidemic where the stakes are high and the conditions for teaching and training are far from optimal. We recommend that educational interventional studies such as randomised controlled trials are performed before another pandemic happens in order to gather and establish evidence-based educational practices that will best equip and certify HCW with the competences needed in the front lines.

Strengths and limitations

A strength of this review is the inclusion of educational interventional studies in the last 20 years, providing an overview of the currently published training programmes for HCW and their evidence. A limitation relates to the exclusion of descriptive studies reporting on the development of training programmes without evaluation. Many of the included studies were not conducted to the highest standards in medical education. We also think that there is a substantial educational effort that goes unreported. Another limitation is the exclusion of non-English language studies which could have helped answer the first research question given that most of the reports concerning viral epidemics come from non-English speaking nations. Finally, we did not include studies that solely evaluated organisational or system-wide impact of interventions because we aimed in this review to focus on how to train HCW rather than how to improve systems through training.

Conclusion

Published educational interventional studies in relation to training during viral epidemics demonstrate a variety of educational content, design, strategies and modes of delivery. Overall, the included studies consistently reported positive benefits of any structured training intervention including positive effects on confidence and knowledge. However, there are very few studies evaluating that these training efforts transfer into improved clinical performance and better patient outcomes. Development and implementation of evidence-based training programmes that can be easily adapted locally are required for the medical community to be well prepared for the next viral epidemic outbreak.

Data availability statement

All data relevant to the study are included in the article or uploaded as supplementary information. An overview of the educational interventional studies included in this systematic review regarding training and education of healthcare workers during viral epidemics including characteristics and general description is uploaded as a supplementary information (Table S1). No additional data available.

Ethics statements

Ethics approval

This review did not involve patients and was therefore exempt from ethical approval according to Danish legislation.

Acknowledgments

The authors sincerely thank Jonathan Lawaetz for developing the data extraction form in RedCap, and for organising the data derived from the system.

References

Supplementary materials

  • Supplementary Data

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Footnotes

  • Contributors All authors have contributed substantially from conception to writing the final version of the manuscript. All authors (LJN, LR, LK and SA) were involved in the conception and design of the study. LJN and SA performed the systematic search, including review and screening for inclusion, while LR and LK participated in resolution of disagreements. LJN, LR, LK and SA were involved in the analysis, synthesis and interpretation of the data. LJN wrote the first draft of the paper with supervision from SA and reviewed by LR and LK. All authors were involved in the revision of the manuscript for relevant scientific content and have approved the final version of the manuscript. All authors are accountable for the accuracy and integrity of this work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.

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