Protocol for thiamine and folic acid in the treatment of cognitive impairment in maintenance haemodialysis patients: a prospective, randomised, placebo-controlled, double-blind, multicentre study

Renhua Lu; Le-Yi Gu; Weiming Zhang; Yongping Guo; Xiujuan Zang; Yan Zhou; Ling Yu; Shuting Pan; Huihua Pang; Shang Liu; Kewei Xie; Ping Li; Xiaojun Zeng; Yifei Lu

doi:10.1136/bmjopen-2021-050605

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Urology

Protocol

Protocol for thiamine and folic acid in the treatment of cognitive impairment in maintenance haemodialysis patients: a prospective, randomised, placebo-controlled, double-blind, multicentre study

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Renhua Lu Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Le-Yi Gu Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, ChinaClinical Center for Investigation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Weiming Zhang Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Yongping Guo Department of Nephrology, Shanghai Sixth Peoples Hospital, Shanghai, China PubMed articles Google scholar articles
Xiujuan Zang Department of Nephrology, Shanghai Songjiang District Central Hospital, Shanghai, China PubMed articles Google scholar articles
Yan Zhou Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Ling Yu Department of Neurology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Shuting Pan Clinical Center for Investigation, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Huihua Pang Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Shang Liu Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Kewei Xie Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Ping Li Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Xiaojun Zeng Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China PubMed articles Google scholar articles
Yifei Lu Department of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articles Google scholar articles

Correspondence to Dr Le-Yi Gu; guleyi{at}aliyun.com

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Lu R, Gu L, Zhang W, et al

Protocol for thiamine and folic acid in the treatment of cognitive impairment in maintenance haemodialysis patients: a prospective, randomised, placebo-controlled, double-blind, multicentre study

BMJ Open 2021;11:e050605. doi: 10.1136/bmjopen-2021-050605

Publication history

Received February 26, 2021
Accepted November 22, 2021
First published December 14, 2021.

Online issue publication

May 16, 2023

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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