Introduction Treatment of distal radius fractures (DRFs) aims to restore anatomic position of the fracture fragments and congruity of the articular surface to optimise functional outcomes and prevent osteoarthritis in the long term. While ligament injury of the wrist is often associated with DRFs and sole ligament injuries of the wrist lead to osteoarthritis, it is plausible that concomitant ligament injury in DRFs may aggravate degenerative changes of the wrist. The relationship between concomitant ligament injury and post-traumatic osteoarthritis in patients with DRFs is unclear. This study aims to identify the types of associated ligament injury in patients with a DRF and to elucidate the association of ligament injury on the development of post-traumatic osteoarthritis.
Methods and analysis This protocol is written in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P) guidelines. An electronic search in MEDLINE, Embase, Web of Science, Cochrane Central Register of Trials and Google Scholar has been created and performed by a Health Sciences librarian with expertise in systematic review searching. Original research articles in English literature, which report on concomitant ligament injury of the wrist in relation to post-traumatic osteoarthritis, patient-reported outcome measures or clinician-reported outcome measures in patients (aged ≥18 years) with DRFs will be included. Two reviewers will independently screen and appraise articles and perform data extraction. In case of any disagreements, a third reviewer will be consulted. A systematic qualitative synthesis will be performed using text and tables.
Ethics and dissemination No ethical approval is required, since this is a protocol for a systematic review. The systematic review will be submitted for publication in a peer-reviewed scientific journal and for presentation at relevant conferences.
PROSPERO registration number CRD42020165007.
- hand & wrist
- trauma management
- orthopaedic & trauma surgery
- musculoskeletal disorders
- trauma management
- adult surgery
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Contributors MES conceived the idea of the study, contributed to the development of the selection criteria, the risk of bias assessment strategy and data extraction criteria, drafted the manuscript of the protocol, will perform the selection process and data collection as an independent reviewer, and will draft the manuscript of the systematic review. GAK provided expertise on osteoarthritis of hand and wrist, contributed to the development of the selection criteria, the risk of bias assessment strategy, data extraction criteria and is the third reviewer in case of any disagreements during the selection and data extraction process. WMB developed the search strategy and provided expertise on the methodology. JWC provided expertise on osteoarthritis of hand and wrist, contributed to the development of the selection criteria, the risk of bias assessment strategy and data extraction criteria. NMCM contributed to the development of the selection criteria, the risk of bias assessment strategy and data extraction criteria. All authors read and approved the final manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.
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