Introduction In October 2018, the Substance Abuse and Mental Health Services Administration funded 21 sites throughout the USA to develop, implement and evaluate specialised care programmes for individuals at clinical high risk for developing a psychotic disorder (CHR-P). Per the funding requirements, such programmes were required to provide ‘step-based care’—a model in which individuals are initially provided with low-intensity, non-psychosis-specific and more benign (ie, least side effects) interventions and only progress onto higher-intensity, psychosis-specific interventions with a greater risk of more severe side effects should they not meet a priori criteria for clinical response to such lower-intensity interventions. Here, we outline the evaluation component of the step-based care programme for individuals at CHR-P at The Ohio State University Early Psychosis Intervention Center (EPICENTER).
Methods and analyses The EPICENTER CHR-P programme provides a step-based care model comprising psychotherapy, medication management, family support/education, peer support and vocational/educational support. All participants who opt to receive care at the EPICENTER will complete a standardised assessment battery as part of usual care. This battery will be administered on enrolment and will be re-administered at 6-month intervals throughout individuals’ participation in EPICENTER clinical services. Participants will have the opportunity to allow for data from these usual care assessments to be used as part of an evaluation project for this new clinical service. The primary outcome for this evaluation project is time to remission of symptomatic and functional deficits commonly experienced by individuals at CHR-P. Participants will also have the opportunity to participate in a supplemental research project designed to further evaluate treatment outcomes and patient characteristics among individuals participating in EPICENTER clinical services.
Ethics and dissemination This project was approved by The Ohio State University Institutional Review Board. Results from this project will be disseminated through publications and presentations.
Trial registration number NCT03970005; Pre-results.
- schizophrenia & psychotic disorders
- mental health
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Statistics from Altmetric.com
Contributors NJKB, HG, WS, GL, KC, JP, NS, HW and AM made substantial contributions to the conception and design of the work. NJKB drafted the manuscript, and HG, WS, GL, KC, JP, NS, HW and AM revised the manuscript for important intellectual content. NJKB, HG, WS, GL, KC, JP, NS, HW and AM approved the final version of the manuscript and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Funding This work was supported by the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) grant numbers (SM081154-01 and SM081154-01M001) as well as through cost matching funds provided by the Alcohol, Drug and Mental Health Board of Franklin County, Ohio and The Ohio State University College of Medicine.
Competing interests All authors reports grants from SAMHSA during the conduct of the study. NJKB and AM have completed paid and unpaid consultation for the Institute for Mental Health Research (IMHR) in helping support the launch of specialised clinic for individuals with first-episode psychosis in Phoenix, Arizona.
Patient consent for publication Not required.
Ethics approval This study was approved by The Ohio State University Institutional Review Board (IRB Protocol Number: 2018H0503).
Provenance and peer review Not commissioned; externally peer reviewed.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.