Respiratory medicine

Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study
Hiroaki Ogata, Yoichiro Hirakawa, Koichiro Matsumoto, Jun Hata, Daigo Yoshida, Satoru Fukuyama, Hiromasa Inoue, Takanari Kitazono, Toshiharu Ninomiya, Yoichi Nakanishi

BMJ Open Mar 2019, 9 (3) e023673; DOI: 10.1136/bmjopen-2018-023673
Assessment of breath volatile organic compounds in acute cardiorespiratory breathlessness: a protocol describing a prospective real-world observational study
Wadah Ibrahim, Michael Wilde, Rebecca Cordell, Dahlia Salman, Dorota Ruszkiewicz, Luke Bryant, Matthew Richardson, Robert C Free, Bo Zhao, Ahmed Yousuf, Christobelle White, Richard Russell, Sheila Jones, Bharti Patel, Asia Awal, Rachael Phillips, Graham Fowkes, Teresa McNally, Clare Foxon, Hetan Bhatt, Rosa Peltrini, Amisha Singapuri, Beverley Hargadon, Toru Suzuki, Leong L Ng, Erol Gaillard, Caroline Beardsmore, Kimuli Ryanna, Hitesh Pandya, Tim Coates, Paul S Monks, Neil Greening, Christopher E Brightling, Paul Thomas, Salman Siddiqui

BMJ Open Mar 2019, 9 (3) e025486; DOI: 10.1136/bmjopen-2018-025486
Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial
Chandrasekaran Padmapriyadarsini, Perumal K Bhavani, Mohan Natrajan, Chinnayan Ponnuraja, Hemanth Kumar, Sivaramakrishnan N Gomathy, Randeep Guleria, Shaheed M Jawahar, Manjula Singh, Tanjore Balganesh, Soumya Swaminathan

BMJ Open Mar 2019, 9 (3) e024363; DOI: 10.1136/bmjopen-2018-024363
Protocol for a systematic literature review and network meta-analysis of the clinical benefit of inhaled maintenance therapies in chronic obstructive pulmonary disease
Adam Lewis, Eleanor L Axson, James Potts, Renelle Tarnowska, Helene Vioix, Jennifer K Quint

BMJ Open Feb 2019, 9 (2) e025048; DOI: 10.1136/bmjopen-2018-025048
Patients and informal caregivers’ experiences of burden of treatment in lung cancer and chronic obstructive pulmonary disease (COPD): a systematic review and synthesis of qualitative research
Kate Alice Lippiett, Alison Richardson, Michelle Myall, Amanda Cummings, Carl R May

BMJ Open Feb 2019, 9 (2) e020515; DOI: 10.1136/bmjopen-2017-020515
Inhaler technique education in elderly patients with asthma or COPD: impact on disease exacerbations—a protocol for a single-blinded randomised controlled trial
Tiago Maricoto, Jaime Correia-de-Sousa, Luís Taborda-Barata

BMJ Open Jan 2019, 9 (1) e022685; DOI: 10.1136/bmjopen-2018-022685
Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study
Ravi Lokwani, Peter A B Wark, Katherine J Baines, Daniel Barker, Jodie L Simpson

BMJ Open Jan 2019, 9 (1) e024330; DOI: 10.1136/bmjopen-2018-024330
Developing an intervention to increase REferral and uptake TO pulmonary REhabilitation in primary care in patients with chronic obstructive pulmonary disease (the REsTORE study): mixed methods study protocol
Frances Early, Patricia Wilson, Christi Deaton, Ian Wellwood, Terry Dickerson, James Ward, Lianne Jongepier, Ruth Barlow, Sally J Singh, John Benson, James Brimicombe, Lois Kim, Hena Haque, Jonathan Fuld

BMJ Open Jan 2019, 9 (1) e024806; DOI: 10.1136/bmjopen-2018-024806
Quality of resistance training description in COPD trials: study protocol for a systematic review
Bennie Westra, Sander de Wolf, Eline bij de Vaate, Monique Legemaat, André Nyberg, Peter Klijn

BMJ Open Jan 2019, 9 (1) e025030; DOI: 10.1136/bmjopen-2018-025030
Delayed antibiotic prescribing for respiratory tract infections: protocol of an individual patient data meta-analysis
Beth Stuart, Hilda Hounkpatin, Taeko Becque, Guiqing Yao, Shihua Zhu, Pablo Alonso-Coello, Attila Altiner, Bruce Arroll, Dankmar Böhning, Jennifer Bostock, Heiner C C Bucher, Mariam de la Poza, Nick A Francis, David Gillespie, Alastair D Hay, Timothy Kenealy, Christin Löffler, Gemma Mas-Dalmau, Laura Muñoz, Kirsty Samuel, Michael Moore, Paul Little

BMJ Open Jan 2019, 9 (1) e026925; DOI: 10.1136/bmjopen-2018-026925

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