Pharmacology and therapeutics

Relative bioavailability of single doses of prolonged-release tacrolimus administered as a suspension, orally or via a nasogastric tube, compared with intact capsules: a phase 1 study in healthy participants
Nasrullah Undre, James Dickinson

BMJ Open Apr 2017, 7 (4) e012252; DOI: 10.1136/bmjopen-2016-012252
Patient perceptions of glucocorticoid side effects: a cross-sectional survey of users in an online health community
Ruth Costello, Rikesh Patel, Jennifer Humphreys, John McBeth, William G Dixon

BMJ Open Apr 2017, 7 (4) e014603; DOI: 10.1136/bmjopen-2016-014603
Evidence of potential bias in a comparison of β blockers and calcium channel blockers in patients with chronic obstructive pulmonary disease and acute coronary syndrome: results of a multinational study
Yaa-Hui Dong, Matthew Alcusky, Vittorio Maio, Jun Liu, Mengdan Liu, Li-Chiu Wu, Chia-Hsuin Chang, Mei-Shu Lai, Joshua J Gagne

BMJ Open Mar 2017, 7 (3) e012997; DOI: 10.1136/bmjopen-2016-012997
Feasibility of melatonin for prevention of delirium in critically ill patients: a protocol for a multicentre, randomised, placebo-controlled study
Lisa Burry, Damon Scales, David Williamson, Jennifer Foster, Sangeeta Mehta, Melanie Guenette, Eddy Fan, Michael Detsky, Azar Azad, Francis Bernard, Louise Rose

BMJ Open Mar 2017, 7 (3) e015420; DOI: 10.1136/bmjopen-2016-015420
Impact of changes in pill appearance in the adherence to angiotensin receptor blockers and in the blood pressure levels: a retrospective cohort study
B Lumbreras, E López-Pintor

BMJ Open Mar 2017, 7 (3) e012586; DOI: 10.1136/bmjopen-2016-012586
Understanding the acceptability and adherence to paediatric antiretroviral treatment in the new formulation of pellets (LPV/r): the protocol of a realist evaluation
Ariadna Nebot Giralt, Christiana Nöstlinger, Janice Lee, Olawale Salami, Marc Lallemant, Onyango Ouma, Isaac Nyamongo, Bruno Marchal

BMJ Open Mar 2017, 7 (3) e014528; DOI: 10.1136/bmjopen-2016-014528
Trajectories of CKD-MBD biochemical parameters over a 2-year period following diagnosis of secondary hyperparathyroidism: a pharmacoepidemiological study
Pierre Filipozzi, Carole Ayav, Willy Ngueyon Sime, Emmanuelle Laurain, Michèle Kessler, Laurent Brunaud, Luc Frimat

BMJ Open Mar 2017, 7 (3) e011482; DOI: 10.1136/bmjopen-2016-011482
Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis
Kerensa T Houghton, Alexandra Forrest, Amine Awad, Lauren Z Atkinson, Sarah Stockton, Paul J Harrison, John R Geddes, Andrea Cipriani

BMJ Open Mar 2017, 7 (3) e013433; DOI: 10.1136/bmjopen-2016-013433
Risk of tuberculosis in patients treated with TNF-α antagonists: a systematic review and meta-analysis of randomised controlled trials
Zheng Zhang, Wei Fan, Gui Yang, Zhigao Xu, June Wang, Qingyuan Cheng, Mingxia Yu

BMJ Open Mar 2017, 7 (3) e012567; DOI: 10.1136/bmjopen-2016-012567
RCT of the effect of berryfruit polyphenolic cultivar extract in mild steroid-naive asthma: a cross-over, placebo-controlled study
Sharon Power, Mathew Williams, Alex Semprini, Claire Munro, Rachel Caswell-Smith, Janine Pilcher, Mark Holliday, James Fingleton, Jacquie Harper, Roger Hurst, Mark Weatherall, Richard Beasley, Irene Braithwaite

BMJ Open Mar 2017, 7 (3) e013850; DOI: 10.1136/bmjopen-2016-013850

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