Intensive care

The effect of blinding on estimates of mortality in randomised clinical trials of intensive care interventions: protocol for a systematic review and meta-analysis
Carl Thomas Anthon, Anders Granholm, Anders Perner, Jon Henrik Laake, Morten Hylander Møller

BMJ Open Jul 2017, 7 (7) e016187; DOI: 10.1136/bmjopen-2017-016187
Research protocol for platelets in out-of-hospital cardiac arrest: an observational, case-controlled, feasibility study to assess coagulation and platelet function abnormalities with ROTEM following out-of-hospital cardiac arrest (PoHCAR)
Agnieszka Skorko, Matthew Thomas, Andrew Mumford, Thomas Johnson, Elinor Griffiths, Rosemary Greenwood, Jonathan Benger

BMJ Open Jul 2017, 7 (7) e015663; DOI: 10.1136/bmjopen-2016-015663
Corticosteroids in sepsis: an updated systematic review and meta-analysis (protocol)
Bram Rochwerg, Simon Oczkowski, Reed Alexander Siemieniuk, Kusum Menon, Wojciech Szczeklik, Shane English, Thomas Agoritsas, Emilie Belley-Cote, Frédérick D’Aragon, Waleed Alhazzani, Erick Duan, Kira Gossack-Keenan, Jon Sevransky, Per Vandvik, Bala Venkatesh, Gordon Guyatt, Djillali Annane

BMJ Open Jun 2017, 7 (6) e016847; DOI: 10.1136/bmjopen-2017-016847
Efficacy of non-invasive ventilation and oxygen therapy on immunocompromised patients with acute hypoxaemic respiratory failure: protocol for a systematic review and meta-analysis of randomised controlled trials
Zongru Li, Tao Wang, Yi Yang, Lixi Zhang, Meng Wang, Gang Liu, Kun He, Juhong Shi, Jianqiang He, Yong Ma, Yi Li, Huadong Zhu, Xuezhong Yu

BMJ Open Jun 2017, 7 (6) e015335; DOI: 10.1136/bmjopen-2016-015335
Effect of corticosteroid administration on neurologically deceased organ donors and transplant recipients: a systematic review and meta-analysis
Frédérick D'Aragon, Emilie Belley-Cote, Arnav Agarwal, Anne-Julie Frenette, Francois Lamontagne, Gordon Guyatt, Sonny Dhanani, Maureen O Meade

BMJ Open Jun 2017, 7 (6) e014436; DOI: 10.1136/bmjopen-2016-014436
The predictive value of serial changes in diaphragm function during the spontaneous breathing trial for weaning outcome: a study protocol
Pengmin Zhou, Zhongheng Zhang, Yucai Hong, Huabo Cai, Hui Zhao, Peifeng Xu, Yiming Zhao, Shengping Lin, Xuchang Qin, JiaWei Guo, Yun Pan, Junru Dai

BMJ Open Jun 2017, 7 (6) e015043; DOI: 10.1136/bmjopen-2016-015043
Exploring the components of physician volunteer engagement: a qualitative investigation of a national Canadian simulation-based training programme
Aimee J Sarti, Stephanie Sutherland, Angele Landriault, Kirk DesRosier, Susan Brien, Pierre Cardinal

BMJ Open Jun 2017, 7 (6) e014303; DOI: 10.1136/bmjopen-2016-014303
A multicentre, randomised controlled, non-inferiority trial, comparing nasal high flow with nasal continuous positive airway pressure as primary support for newborn infants with early respiratory distress born in Australian non-tertiary special care nurseries (the HUNTER trial): study protocol
Brett J Manley, Calum T Roberts, Gaston R B Arnolda, Ian M R Wright, Louise S Owen, Kim M Dalziel, Jann P Foster, Peter G Davis, Adam G Buckmaster

BMJ Open Jun 2017, 7 (6) e016746; DOI: 10.1136/bmjopen-2017-016746
Red blood cell distribution width as a risk factor for inhospital mortality in obstetric patients admitted to an intensive care unit: a single centre retrospective cohort study
Yufeng Chu, Zhongshang Yuan, Mei Meng, Haiyan Zhou, Chunting Wang, Gong Yang, Hongsheng Ren

BMJ Open Jun 2017, 7 (6) e012849; DOI: 10.1136/bmjopen-2016-012849
The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial
Antje Neubert, Manuel Alberto Baarslag, Monique van Dijk, Joost van Rosmalen, Joseph F Standing, Yucheng Sheng, Wolfgang Rascher, Deborah Roberts, Jackie Winslade, Louise Rawcliffe, Sara M Hanning, Tuuli Metsvaht, Viviana Giannuzzi, Peter Larsson, Pavla Pokorná, Alessandra Simonetti, Dick Tibboel

BMJ Open Jun 2017, 7 (6) e016031; DOI: 10.1136/bmjopen-2017-016031

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