Cardiovascular medicine

Bleeding and thrombotic complications during treatment with direct oral anticoagulants or vitamin K antagonists in venous thromboembolic patients included in the prospective, observational START2-register
Gualtiero Palareti, Emilia Antonucci, Cristina Legnani, Daniela Mastroiacovo, Daniela Poli, Paolo Prandoni, Alberto Tosetto, Vittorio Pengo, Sophie Testa, Walter Ageno

BMJ Open Nov 2020, 10 (11) e040449; DOI: 10.1136/bmjopen-2020-040449
Sex-specific temporal trends in ambulatory heart failure incidence, mortality and hospitalisation in Ontario, Canada from 1994 to 2013: a population-based cohort study
Louise Y Sun, Lisa M Mielniczuk, Peter P Liu, Rob S Beanlands, Sharon Chih, Ross Davies, Thais Coutinho, Douglas S Lee, Peter C Austin, Anan Bader Eddeen, Jack V Tu

BMJ Open Nov 2020, 10 (11) e044126; DOI: 10.1136/bmjopen-2020-044126
Strategies for enhancing the initiation of cholesterol lowering medication among patients at high cardiovascular disease risk: a qualitative descriptive exploration of patient and general practitioners’ perspectives on a facilitated relay intervention in Alberta, Canada
David J T Campbell, Rachelle C W Lee-Krueger, Kerry McBrien, Todd Anderson, Hude Quan, Alexander A Leung, Guanmin Chen, Mingshan Lu, Christopher Naugler, Sonia Butalia

BMJ Open Nov 2020, 10 (11) e038469; DOI: 10.1136/bmjopen-2020-038469
Improving the Safety and Continuity Of Medicines management at Transitions of care (ISCOMAT): protocol for a process evaluation of a cluster randomised control trial
Catherine Powell, Liz Breen, Beth Fylan, Hanif Ismail, Sarah L Alderson, Chris P Gale, Peter Gardner, Amanda J Farrin, David P Alldred

BMJ Open Nov 2020, 10 (11) e040493; DOI: 10.1136/bmjopen-2020-040493
Comparing efficacy and safety in catheter ablation strategies for atrial fibrillation: protocol of a network meta-analysis of randomised controlled trials
Emmanouil Charitakis, Lars O Karlsson, Kostantinos Rizas, Henrik Almroth, Anders Hassel Jönsson, Jonas Schweiler, Skevos Sideris, Dimitrios Tsartsalis, Elena Dragioti, Anna Chaimani

BMJ Open Nov 2020, 10 (11) e041819; DOI: 10.1136/bmjopen-2020-041819
Does intermittent exposure to high altitude increase the risk of cardiovascular disease in workers? A systematic narrative review
Jerónimo Aragón-Vela, Jacob Bejder, Jesús R Huertas, Julio Plaza-Diaz, Nikolai B Nordsborg

BMJ Open Nov 2020, 10 (11) e041532; DOI: 10.1136/bmjopen-2020-041532
Consumption and market share of cholesterol-lowering drugs in high-risk patients before and after the release of the 2013 ACC/AHA cholesterol guidelines: a retrospective observational study
Tzu-Tsen Kuo, Yaw-Bin Huang, Ching-Jung Hsieh

BMJ Open Nov 2020, 10 (11) e036769; DOI: 10.1136/bmjopen-2020-036769
Effect of spironolactone on cardiovascular morbidity and mortality in patients with hypertension and glucose metabolism disorders (ESCAM): a study protocol for a pragmatic randomised controlled trial
Nanfang Li, Mengyue Lin, Mulalibieke Heizhati, Lin Wang, Qin Luo, Yuanyuan Li, Jina Yili, Jing Hong, Xiaoguang Yao, Qing Zhu

BMJ Open Nov 2020, 10 (11) e038694; DOI: 10.1136/bmjopen-2020-038694
Clinical Surveillance vs. Anticoagulation For low-risk patiEnts with isolated SubSegmental Pulmonary Embolism: protocol for a multicentre randomised placebo-controlled non-inferiority trial (SAFE-SSPE)
Christine Baumgartner, Frederikus A Klok, Marc Carrier, Andreas Limacher, Jeanne Moor, Marc Righini, Jürg-Hans Beer, Martina Peluso, Damiana Rakovic, Menno V Huisman, Drahomir Aujesky

BMJ Open Nov 2020, 10 (11) e040151; DOI: 10.1136/bmjopen-2020-040151
Clinical and biological determinants of P-wave duration: cross-sectional data from the population-based CoLaus|PsyCoLaus study
Federica Bocchi, Pedro Marques-Vidal, Etienne Pruvot, Gerard Waeber, Peter Vollenweider, David Gachoud

BMJ Open Nov 2020, 10 (11) e038828; DOI: 10.1136/bmjopen-2020-038828

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