Anaesthesia

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery
Mark R Edwards, Gordon Forbes, Neil MacDonald, Vladislav Berdunov, Borislava Mihaylova, Priyanthi Dias, Ann Thomson, Michael PW Grocott, Monty G Mythen, Mike A Gillies, Michael Sander, Tuong D Phan, Lisbeth Evered, Duminda N Wijeysundera, Stuart A McCluskey, Cesar Aldecoa, Javier Ripollés-Melchor, Christoph K Hofer, Hussein Abukhudair, Wojciech Szczeklik, Ioana Grigoras, Ludhmila A Hajjar, Brennan C Kahan, Rupert M Pearse

BMJ Open Jan 2019, 9 (1) e023455; DOI: 10.1136/bmjopen-2018-023455
Protocol for a prospective observational study to develop a frailty index for use in perioperative and critical care
Jai N Darvall, Sabine Braat, David A Story, Kate Greentree, Tony Bose, Joel Loth, Wen K Lim

BMJ Open Jan 2019, 9 (1) e024682; DOI: 10.1136/bmjopen-2018-024682
Randomised controlled study comparing general and spinal anaesthesia with and without a tourniquet on the outcomes of total knee arthroplasty: study protocol
Mikko Tuomas Rantasalo, Riku Palanne, Katarina Juutilainen, Pekka Kairaluoma, Rita Linko, Elina Reponen, Teemu Helkamaa, Anne Vakkuri, Klaus T Olkkola, Rami Madanat, Noora Kati Annukka Skants

BMJ Open Dec 2018, 8 (12) e025546; DOI: 10.1136/bmjopen-2018-025546
Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses
Kapil Gupta, Mahesh Nagappa, Arun Prasad, Lusine Abrahamyan, Jean Wong, Toby N Weingarten, Frances Chung

BMJ Open Dec 2018, 8 (12) e024086; DOI: 10.1136/bmjopen-2018-024086
Determining correct tracheal tube insertion depth by measuring distance between endotracheal tube cuff and vocal cords by ultrasound in Chinese adults: a prospective case-control study
Xuanling Chen, Wenwen Zhai, Zhuoying Yu, Jiao Geng, Min Li

BMJ Open Dec 2018, 8 (12) e023374; DOI: 10.1136/bmjopen-2018-023374
Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review
Vanisha Patel, Rita Champaneria, Janine Dretzke, Joyce Yeung

BMJ Open Dec 2018, 8 (12) e020757; DOI: 10.1136/bmjopen-2017-020757
Clinical indicators for reporting the effectiveness of patient quality and safety-related interventions: a protocol of a systematic review and Delphi consensus process as part of the international Standardised Endpoints for Perioperative Medicine initiative (StEP)
Sohail Bampoe, Tim Cook, Lee Fleisher, Michael P W Grocott, Mark Neuman, David Story, Paul Myles, Guy Haller

BMJ Open Nov 2018, 8 (11) e023427; DOI: 10.1136/bmjopen-2018-023427
Perioperative application of dexmedetomidine for postoperative systemic inflammatory response syndrome in patients undergoing percutaneous nephrolithotomy lithotripsy: results of a randomised controlled trial
Yingqing Deng, Fang Tan, Xiaoliang Gan, Xiaoyun Li, Mian Ge, Chulian Gong, Ziqing Hei, Qianqian Zhu, Shaoli Zhou

BMJ Open Nov 2018, 8 (11) e019008; DOI: 10.1136/bmjopen-2017-019008
Mixed-methods evaluation of the Perioperative Medicine Service for High-Risk Patients Implementation Pilot (POMSHIP): a study protocol
David Walker, Duncan Wagstaff, Dermot McGuckin, Cecilia Vindrola-Padros, Nicholas Swart, Stephen Morris, Sonya Crowe, Naomi J Fulop, S Ramani Moonesinghe

BMJ Open Oct 2018, 8 (10) e021647; DOI: 10.1136/bmjopen-2018-021647
Protocol for a randomised, double-blind, placebo-controlled trial to explore the effect of tramadol in the prevention of postpartum depression (ETPPD)
Guangyou Duan, Zhuoxi Wu, Peng Zhao, Jing Peng, Zhengqiong Chen, Qingling Zhang, Rufu Xu, Hong Li

BMJ Open Oct 2018, 8 (10) e022538; DOI: 10.1136/bmjopen-2018-022538

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