User profiles for "author:Patrick MacPhail"
 | Patrick MacPhailEmeritus Professor Verified email at witshealth.co.za Cited by 3005 |
Dietary iron overload as a risk factor for hepatocellular carcinoma in Black Africans
E Mandishona, PA MacPhail, VR Gordeuk… - Hepatology, 1998 - journals.lww.com
Although the iron-loading disease, hereditary hemochromatosis, has a strong causal
association with hepatocellular carcinoma (HCC), the carcinogenic potential of dietary iron …
association with hepatocellular carcinoma (HCC), the carcinogenic potential of dietary iron …
Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene☆
VR Gordeuk, A Caleffi, E Corradini, F Ferrara… - Blood Cells, Molecules …, 2003 - Elsevier
The product of the SLC40A1 gene, ferroportin 1, is a main iron export protein. Pathogenic
mutations in ferroportin 1 lead to an autosomal dominant hereditary iron overload syndrome …
mutations in ferroportin 1 lead to an autosomal dominant hereditary iron overload syndrome …
[HTML][HTML] Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa
Background The World Health Organization estimates that in sub-Saharan Africa about 4
million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008 …
million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008 …
Using vital registration data to update mortality among patients lost to follow‐up from ART programmes: evidence from the Themba Lethu Clinic, South Africa
Objective To estimate the rates of mortality in patients lost to follow‐up (LTFU) from a large
urban public sector HIV clinic in South Africa. Methods We compared vital status using the …
urban public sector HIV clinic in South Africa. Methods We compared vital status using the …
[HTML][HTML] Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial
SE Krown, CB Moser, P MacPhail, RM Matining… - The Lancet, 2020 - thelancet.com
Background Optimal treatment regimens for AIDS-associated Kaposi sarcoma, a frequent
contributor to morbidity and mortality among people with HIV, have not been systematically …
contributor to morbidity and mortality among people with HIV, have not been systematically …
The prevalence of hepatitis B co-infection in a South African urban government HIV clinic
C Firnhaber, A Reyneke, D Schulze… - South African Medical …, 2008 - journals.co.za
Objective. There are an estimated 350 million hepatitis B carriers worldwide. In South Africa
the prevalence of mono-infection with hepatitis B has been estimated to range from 1% in …
the prevalence of mono-infection with hepatitis B has been estimated to range from 1% in …
Mortality after failure of antiretroviral therapy in sub‐Saharan Africa
O Keiser, H Tweya, P Braitstein, F Dabis… - Tropical medicine & …, 2010 - Wiley Online Library
Objective To assess the outcome of patients who experienced treatment failure with
antiretrovirals in sub‐Saharan Africa. Methods Analysis of 11 antiretroviral therapy (ART) …
antiretrovirals in sub‐Saharan Africa. Methods Analysis of 11 antiretroviral therapy (ART) …
Accuracy of WHO CD4 cell count criteria for virological failure of antiretroviral therapy
Objectives To examine the accuracy of the World Health Organization immunological criteria
for virological failure of antiretroviral treatment. Methods Analysis of 10 treatment …
for virological failure of antiretroviral treatment. Methods Analysis of 10 treatment …
Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring …
Objective: To compare clinical, immunologic and virologic outcomes among stable HIV-
positive patients down-referred to a nurse-managed primary healthcare clinic (PHC) for …
positive patients down-referred to a nurse-managed primary healthcare clinic (PHC) for …
Transmission of Kaposi sarcoma-associated herpesvirus between mothers and children in a South African population
BI Malope, RM Pfeiffer, G Mbisa, L Stein… - JAIDS Journal of …, 2007 - journals.lww.com
Background: To assess whether Kaposi sarcoma-associated herpesvirus (KSHV) with or
without HIV coinfection in South African mothers is associated with higher KSHV …
without HIV coinfection in South African mothers is associated with higher KSHV …