[HTML][HTML] Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review

U Ravnskov, DM Diamond, R Hama, T Hamazaki… - BMJ open, 2016 - bmjopen.bmj.com
Objective It is well known that total cholesterol becomes less of a risk factor or not at all for all-
cause and cardiovascular (CV) mortality with increasing age, but as little is known as to …

[HTML][HTML] Homocysteine, vitamins, and vascular disease prevention

KS McCully - The American journal of clinical nutrition, 2007 - Elsevier
In mid-20th century United States, deaths from vascular disease reached a peak incidence
in 1955, but little was known about the underlying causes of this epidemic of disease. The …

Chemical pathology of homocysteine. IV. Excitotoxicity, oxidative stress, endothelial dysfunction, and inflammation

KS McCully - Annals of Clinical & Laboratory Science, 2009 - Assoc Clin Scientists
This review considers recent advances in the chemical pathology of homocysteine in
atherogenesis, oxidative metabolism, and carcinogenesis. Homocysteine is a potent …

Homocysteine theory of arteriosclerosis

KS McCully, RB Wilson - Atherosclerosis, 1975 - Elsevier
Arteriosclerotic plaques were found in the aorta and arteries of rabbits given homocysteine
thiolactone, methionine or homocysteic acid, both parenterally and in a synthetic diet …

Homocysteine and the pathogenesis of atherosclerosis

KS McCully - Expert review of clinical pharmacology, 2015 - Taylor & Francis
The homocysteine theory of arteriosclerosis was discovered by study of arteriosclerotic
plaques occurring in homocystinuria, a disease caused by deficiencies of cystathionine …

Chemical pathology of homocysteine. I. Atherogenesis

KS McCully - Annals of Clinical & Laboratory Science, 1993 - Assoc Clin Scientists
The atherogenic properties of homocysteine were discovered by observation of
arteriosclerosis in children with homocystinuria caused by inherited deficiency of three …

LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature

U Ravnskov, M de Lorgeril, DM Diamond… - Expert review of …, 2018 - Taylor & Francis
Introduction: For half a century, a high level of total cholesterol (TC) or low-density
lipoprotein cholesterol (LDL-C) has been considered to be the major cause of …

Homocysteine metabolism and the oxidative modification of proteins and lipids

AJ Olszewski, KS McCully - Free Radical Biology and Medicine, 1993 - Elsevier
Altered homocysteine metabolism is implicated as a pathogenic factor in atherogenesis,
neoplasia, and aging. Hereditary enzymatic deficiencies and nutritional deficiencies of …

[PDF][PDF] Homocysteine metabolism, atherosclerosis, and diseases of aging

KS McCully - Compr Physiol, 2015 - researchgate.net
The importance of homocysteine in vascular function and arteriosclerosis was discovered by
demonstration of arteriosclerotic plaques in children with homocystinuria caused by …

Production of arteriosclerosis by homocysteinemia.

KS McCully, BD Ragsdale - The American journal of pathology, 1970 - ncbi.nlm.nih.gov
Materials and Methods Production of Homocysteinemia Thirty milligrams of dl-homocysteine
thiolactone (Calbiochem), 1 mg/ml in 5% dextrose-water, were administered subcutaneously …