MicroRNA-494 reduces ATF3 expression and promotes AKI

YF Lan, HH Chen, PF Lai, CF Cheng… - Journal of the …, 2012 - journals.lww.com
MicroRNA-494 mediates apoptosis and necrosis in several types of cells, but its renal target
and potential role in AKI are unknown. Here, we found that microRNA-494 binds to the 3 …

[HTML][HTML] MicroRNAs as biomarkers and therapeutic targets in inflammation-and ischemia-reperfusion-related acute renal injury

YL Wu, HF Li, HH Chen, H Lin - International journal of molecular …, 2020 - mdpi.com
Acute kidney injury (AKI), caused mainly by ischemia-reperfusion, sepsis, or nephrotoxins
(such as contrast medium), is identified by an abrupt decline in kidney function and is …

[HTML][HTML] Emergent roles of circular RNAs in metabolism and metabolic disorders

YL Wu, HF Li, HH Chen, H Lin - International journal of molecular …, 2022 - mdpi.com
Circular RNAs (circRNAs) are an emerging group of long non-coding RNAs (lncRNAs) and
have attracted attention again according to the progress in high-throughput sequencing in …

[HTML][HTML] Mechanism and molecular determinant for regulation of rabbit transient receptor potential type 5 (TRPV5) channel by extracellular pH

BI Yeh, TJ Sun, JZ Lee, HH Chen, CL Huang - Journal of Biological …, 2003 - ASBMB
The transient receptor potential type 5 (TRPV5) channel is present in kidney and intestine
and important for transepithelial (re) absorption of calcium in these tissues. We report that in …

The association between plasma selenium and chronic kidney disease related to lead, cadmium and arsenic exposure in a Taiwanese population

CY Wu, CS Wong, CJ Chung, MY Wu, YL Huang… - Journal of hazardous …, 2019 - Elsevier
This study aimed to determine the interaction of red blood cell cadmium and lead, total
urinary arsenic, and plasma selenium in chronic kidney disease (CKD). We recruited 220 …

Exosomal ATF3 RNA attenuates pro‐inflammatory gene MCP‐1 transcription in renal ischemia‐reperfusion

HH Chen, PF Lai, YF Lan, CF Cheng… - Journal of cellular …, 2014 - Wiley Online Library
Transcriptional repressor activating transcription factor 3 (ATF3) is induced by various stress
stimuli, including inflammation‐induced renal injury. In addition, ATF3 also down‐regulates …

[HTML][HTML] Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3

CF Cheng, HC Ku, JJ Cheng, SW Chao, HF Li… - Communications …, 2019 - nature.com
Billions of people have obesity-related metabolic syndromes such as diabetes and
hyperlipidemia. Promoting the browning of white adipose tissue has been suggested as a …

Multifunctions of excited gold nanoparticles decorated artificial kidney with efficient hemodialysis and therapeutic potential

HC Chen, CY Cheng, HC Lin, HH Chen… - … Applied Materials & …, 2016 - ACS Publications
Chronic kidney disease (CKD) is inflammation-related. Patients with chronic renal failure
who undergo hemodialysis (HD) have some acute adverse effects caused by dialysis …

[HTML][HTML] Urinary miR-16 transactivated by C/EBPβ reduces kidney function after ischemia/reperfusion–induced injury

HH Chen, YF Lan, HF Li, CF Cheng, PF Lai, WH Li… - Scientific reports, 2016 - nature.com
Abstract Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is regulated by
transcriptional factors and microRNAs (miRs). However, modulation of miRs by …

Prostacyclin-induced peroxisome proliferator-activated receptor-α translocation attenuates NF-κB and TNF-α activation after renal ischemia-reperfusion injury

HH Chen, TW Chen, H Lin - American Journal of …, 2009 - journals.physiology.org
Prostacyclin and peroxisome proliferator-activated receptors (PPAR) protect against
ischemia-reperfusion (I/R) injury by the induction of an anti-inflammatory pathway. In this …