Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion

EJ Sharples, N Patel, P Brown, K Stewart… - Journal of the …, 2004 - journals.lww.com
Erythropoietin (EPO) is upregulated by hypoxia and causes proliferation and differentiation
of erythroid progenitors in the bone marrow through inhibition of apoptosis. EPO receptors …

Pancreas transplantation: past, present, future

S Dholakia, S Mittal, I Quiroga, J Gilbert… - The American journal of …, 2016 - Elsevier
Diabetes is the pandemic disease of the modern era, with 10% of these patients having type
1 diabetes mellitus. Despite the prevalence, morbidities, and associated financial burden …

[HTML][HTML] Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo

NSA Patel, EJ Sharples, S Cuzzocrea, PK Chatterjee… - Kidney international, 2004 - Elsevier
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion
in the mouse kidney in vivo. Background Erythropoietin (EPO) is a potent stimulator of …

The effects of neighbourhood social cohesion on preventing depression and anxiety among adolescents and young adults: rapid review

JJF Breedvelt, H Tiemeier, E Sharples, S Galea… - BJPsych …, 2022 - cambridge.org
Background Research suggests that increasing neighbourhood social cohesion can prevent
mental health problems, including depression and anxiety. However, it is unknown whether …

Erythropoietin in experimental acute renal failure

EJ Sharples, MM Yaqoob - Nephron Experimental Nephrology, 2006 - karger.com
The haematopoietic factor erythropoietin (EPO) has recently been recognized to play a
physiological role in the brain and other tissues. The EPO receptor is present in the …

Coronary artery calcification measured with electron-beam computerized tomography correlates poorly with coronary artery angiography in dialysis patients

EJ Sharples, D Pereira, S Summers… - American Journal of …, 2004 - Elsevier
Background: Coronary artery calcification measured by electron-beam computerized
tomography (EBCT) correlates with plaque burden and vessel stenosis and is predictive of …

Recombinant human erythropoietin protects the liver from hepatic ischemia‐reperfusion injury in the rat

B Sepodes, R Maio, R Pinto, E Sharples… - Transplant …, 2006 - Wiley Online Library
Recently, erythropoietin was shown to have both hematopoietic as well as tissue‐protective
properties. Erythropoietin (EPO) had a protective effect in animal models of cerebral …

[HTML][HTML] Transplantation of kidneys from donors with acute kidney injury: friend or foe?

…, JH van der Heide, J Gilbert, E Sharples… - American Journal of …, 2017 - Elsevier
The gap between supply and demand in kidney transplantation has led to increased use of
marginal kidneys; however, kidneys with acute kidney injury are often declined/discarded …

Erythropoietin attenuates the tissue injury associated with hemorrhagic shock and myocardial ischemia

M Abdelrahman, EJ Sharples, MC McDonald, M Collin… - Shock, 2004 - journals.lww.com
Here we investigate the effects of erythropoietin (EPO) on the tissue/organ injury caused by
hemorrhagic shock (HS), endotoxic shock, and regional myocardial ischemia and …

[HTML][HTML] Sarcoid tubulo-interstitial nephritis: long-term outcome and response to corticosteroid therapy

R Rajakariar, EJ Sharples, MJ Raftery, M Sheaff… - Kidney international, 2006 - Elsevier
Sarcoidosis is a chronic relapsing multi-systemic disorder characterized by the development
of non-caseating granulomas. Granulomatous tubulo-interstitial nephritis is an uncommon …