Abstract
In units that bathe patients daily with chlorhexidine gluconate (CHG), organisms causing central line-associated bloodstream infections (CLABSIs) were more likely to have reduced CHG susceptibility than organisms causing CLABSIs in units that do not bathe patients daily with CHG (86% vs 64%; P = .028). Surveillance is needed to detect reduced CHG susceptibility with widespread CHG use.
Publication types
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Clinical Trial
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Infective Agents, Local / administration & dosage
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Anti-Infective Agents, Local / pharmacology*
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Bacteremia / microbiology*
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Catheter-Related Infections / microbiology*
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Catheterization, Central Venous
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Chlorhexidine / administration & dosage
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Chlorhexidine / analogs & derivatives*
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Chlorhexidine / pharmacology
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Cross Infection / microbiology*
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Drug Resistance, Bacterial / drug effects*
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Gram-Negative Bacteria / drug effects
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Gram-Negative Bacterial Infections / microbiology
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Gram-Positive Bacteria / drug effects
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Gram-Positive Bacterial Infections / microbiology
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Humans
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Microbial Sensitivity Tests
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Prospective Studies
Substances
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Anti-Infective Agents, Local
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chlorhexidine gluconate
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Chlorhexidine