Infirmity and injury complexity are risk factors for surgical-site infection after operative fracture care

Clin Orthop Relat Res. 2011 Sep;469(9):2621-30. doi: 10.1007/s11999-010-1737-2. Epub 2010 Dec 16.

Abstract

Background: Orthopaedic surgical-site infections prolong hospital stays, double rehospitalization rates, and increase healthcare costs. Additionally, patients with orthopaedic surgical-site infections (SSI) have substantially greater physical limitations and reductions in their health-related quality of life. However, the risk factors for SSI after operative fracture care are unclear.

Questions/purpose: We determined the incidence and quantified modifiable and nonmodifiable risk factors for SSIs in patients with orthopaedic trauma undergoing surgery.

Patients and methods: We retrospectively indentified, from our prospective trauma database and billing records, 1611 patients who underwent 1783 trauma-related procedures between 2006 and 2008. Medical records were reviewed and demographics, surgery-specific data, and whether the patients had an SSI were recorded. We determined which if any variables predicted SSI.

Results: Six factors independently predicted SSI: (1) the use of a drain, OR 2.3, 95% CI (1.3-3.8); (2) number of operations OR 3.4, 95% CI (2.0-6.0); (3) diabetes, OR 2.1, 95% CI (1.2-3.8); (4) congestive heart failure (CHF), OR 2.8, 95% CI (1.3-6.5); (5) site of injury tibial shaft/plateau, OR 2.3, 95% CI (1.3-4.2); and (6) site of injury, elbow, OR 2.2, 95% CI (1.1-4.7).

Conclusion: The risk factors for SSIs after skeletal trauma are most strongly determined by nonmodifiable factors: patient infirmity (diabetes and heart failure) and injury complexity (site of injury, number of operations, use of a drain).

Level of evidence: Level II, prognostic study. See the Guideline for Authors for a complete description of levels of evidence.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Boston
  • Diabetes Complications / etiology
  • Drainage / adverse effects
  • Female
  • Fracture Fixation / adverse effects*
  • Fractures, Bone / diagnosis
  • Fractures, Bone / surgery*
  • Health Status Indicators*
  • Heart Failure / complications
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Surgical Wound Infection / etiology*
  • Treatment Outcome
  • Young Adult