Development of asymptomatic pancreatitis with paradoxically high serum clozapine levels in a patient with schizophrenia and the CYP1A2*1F/1F genotype

J Clin Psychopharmacol. 2010 Dec;30(6):737-9. doi: 10.1097/JCP.0b013e3181faa7e3.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / pharmacokinetics
  • Antipsychotic Agents / therapeutic use
  • Clozapine / adverse effects*
  • Clozapine / pharmacokinetics
  • Clozapine / therapeutic use
  • Cytochrome P-450 CYP1A2 / genetics*
  • Female
  • Genotype
  • Humans
  • Hyperglycemia / chemically induced
  • Pancreatitis / chemically induced*
  • Schizophrenia, Paranoid / drug therapy

Substances

  • Antipsychotic Agents
  • Cytochrome P-450 CYP1A2
  • Clozapine