The association of age, gender, body fatness and lifestyle factors with plasma C-reactive protein concentrations in older Taiwanese

J Nutr Health Aging. 2010 Jun;14(6):412-6. doi: 10.1007/s12603-010-0042-9.

Abstract

Objective: This study determined the population distribution of plasma C-reactive protein (CRP) and evaluated its association with age, body fatness status and lifestyle factors in elderly Taiwanese.

Design: A crosssectional-study.

Setting: A population-representative sample. The "1999-2000 Elderly Nutrition and Health Survey in Taiwan".

Participants: 2432 non-institutionalized population-representative Taiwanese, 65 y or older.

Measurements: Plasma CRP-concentrations and factors that impact plasma CRP concentrations.

Results: Results showed that weighting-adjusted plasma CRP concentration (mean +/- SE) was 2.50 +/- 0.10 mg/L for men and 2.70 +/- 0.10 mg/L for women. Cigarette smoking was positively associated with plasma CRP concentrations in both men and women. Age was positively (P < 0.05) but physical activity was negatively (P <0.05) associated with plasma CRP concentrations in men. These associations were not significant in women. Waist circumference but not BMI was significantly (P < 0.05) associated with plasma CRP in women. Both associations were not significant in men. Alcohol drinking and betel nut-chewing were not significantly associated with CRP concentrations.

Conclusion: Results suggest that there are gender-related differences in the degree of association of CRP concentrations with age, waist circumference, BMI and physical activity in older Taiwanese. Results also suggest population-related differences in the strength of many associations when compared to observations made in Western countries. These findings may help delineate the differences in cardiovascular risk among various populations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adiposity
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Body Mass Index
  • C-Reactive Protein / analysis*
  • C-Reactive Protein / metabolism
  • Cross-Sectional Studies
  • Exercise / physiology*
  • Female
  • Geriatric Assessment*
  • Health Surveys
  • Humans
  • Inflammation / blood
  • Life Style
  • Male
  • Sex Factors
  • Smoking / adverse effects
  • Smoking / blood
  • Taiwan
  • Waist Circumference / physiology*

Substances

  • Biomarkers
  • C-Reactive Protein