Musculoskeletal symptoms are a major concern among dental practitioners. Dental students perform the same clinical tasks as dentists in private practice, yet only recently has scientific evidence suggested a relationship between the tasks and musculoskeletal symptoms. This study investigates the clinical tasks that place students at physical risk and the relationship between the tasks and musculoskeletal symptoms. Student perceptions of physical symptoms were established with a questionnaire identifying variables on general health, tasks, physical demands, workload and environment. A total of 61% (358/590) reported that during the past year they experienced musculoskeletal symptoms related to work at dental school (second year (n = 212), third year (n = 201) and fourth year (n = 177)). Of those students, the neck represented 48%, shoulder 31%, back 44% and hands 20% (p < 0.001). Third year students reported the highest occurrence of symptoms in every body area (p < 0.001). Third and fourth year students reported significant relationships between the occurrence of symptoms and equipment utilisation, work efficiency and general health. Further studies are recommended to evaluate types and levels of potential risk factors. A total of 75% of dental practitioners are at risk for developing work-related musculoskeletal disorders. Results from this study have found that dental students were no exception. Third year dental students reported the highest level of musculoskeletal symptoms with the prevalence of pain in the neck, shoulder and lower back.