Health outcomes associated with potentially inappropriate medication use in older adults

Res Nurs Health. 2008 Feb;31(1):42-51. doi: 10.1002/nur.20232.

Abstract

The purpose of this study was to examine the prevalence of potentially inappropriate medication use (PIMs) among community-dwelling older adults and the association between PIMs and health care outcomes. Participants were 17,971 individuals age 65 years and older. PIM use was defined by the Beers criteria. Drug-related problems (DRPs) were defined using ICD-9 codes. Forty percent of the 17,971 individuals filled at least 1 PIM prescription, and 13% filled 2 or more PIM prescriptions. Overall DRP prevalence among those with at least 1 PIM prescription was 14.3% compared to 4.7% in the non-PIM group (p < .001). In conclusion, preventing PIM use may be important for decreasing medication-related problems, which are increasingly being recognized as requiring an integrated interdisciplinary approach.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged* / statistics & numerical data
  • Analysis of Variance
  • Chi-Square Distribution
  • Comorbidity
  • Cost of Illness
  • Drug Prescriptions* / statistics & numerical data
  • Drug Therapy* / statistics & numerical data
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Health Services / economics
  • Health Services / statistics & numerical data
  • Health Services Research
  • Health Status*
  • Humans
  • Insurance Claim Reporting / statistics & numerical data
  • International Classification of Diseases
  • Logistic Models
  • Male
  • Medication Errors* / adverse effects
  • Medication Errors* / statistics & numerical data
  • Nurse's Role
  • Patient Selection
  • Polypharmacy
  • Population Surveillance
  • Prevalence
  • Retrospective Studies
  • Southeastern United States / epidemiology