Postoperative residual paralysis in outpatients versus inpatients

Anesth Analg. 2006 Feb;102(2):426-9. doi: 10.1213/01.ane.0000195543.61123.1f.

Abstract

Postoperative residual paralysis is an important complication of the use of neuromuscular blocking drugs. In this prospective study, the incidence of residual paralysis detected as a train-of-four response <90% was less frequent in surgical outpatients (38%) than inpatients (47%) (P = 0.001). This might have been the result of the more frequent use of mivacurium for outpatients. Before undertaking tracheal extubation, the anesthesiologists had applied clinical criteria (outpatients, 49%; inpatients, 45%), pharmacological reversal (26%, 25%), neuromuscular transmission monitoring (12%, 11%), or a combination of these. None of these measures seemed to reduce the incidence of residual paralysis except for quantitative train-of-four monitoring. Postoperatively, eight individual clinical tests or a sum of these tests were also unable to predict residual paralysis by train-of-four. Although the incidence of residual paralysis was less frequent in surgical outpatients, predictive criteria were not evident.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ambulatory Surgical Procedures*
  • Anesthesia Recovery Period
  • Hospitalization*
  • Humans
  • Inpatients
  • Intubation, Intratracheal
  • Monitoring, Intraoperative
  • Neurologic Examination
  • Neuromuscular Blockade*
  • Neuromuscular Blocking Agents / administration & dosage*
  • Paralysis / drug therapy
  • Paralysis / etiology*
  • Postoperative Complications*
  • Synaptic Transmission

Substances

  • Neuromuscular Blocking Agents