Maternal anaemia and its impact on perinatal outcome

Trop Med Int Health. 2004 Apr;9(4):486-90. doi: 10.1111/j.1365-3156.2004.01222.x.

Abstract

Objective: To find out the relationship between maternal anaemia and perinatal morbidity and mortality.

Method: A cohort of 629 pregnant women was studied from October 2001 to October 2002. Of these, 313 were anaemic (haemoglobin <11 g/dl in labour and on two previous occasions in current pregnancy). A total of 316 women had haemoglobin >11 g/dl at all times in pregnancy and were labelled as non-anaemic. Perinatal outcomes included preterm delivery, low birth weight (LBW) at delivery, intrauterine growth restriction, perinatal mortality, APGAR score at 1 and 5 min, intrauterine foetal demise (IUD).

Results: The risk of preterm delivery and LBW among exposed group was 4 and 1.9 times higher among anaemic women, respectively. Newborns of anaemic mothers had 1.8 times increased risk of having an APGAR score of <5 at 1 min and the risk of IUD was 3.7 times higher for anaemic women.

Conclusion: Low maternal haemoglobin levels are associated with increased risk of preterm delivery, LBW babies, APGAR score <5 at 1 min and IUD.

MeSH terms

  • Adult
  • Anemia*
  • Apgar Score
  • Cohort Studies
  • Developing Countries
  • Female
  • Fetal Death / etiology
  • Humans
  • Infant Mortality
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Pakistan / epidemiology
  • Pregnancy
  • Pregnancy Complications, Hematologic*
  • Pregnancy Outcome*
  • Socioeconomic Factors