Patients' perspectives on statin therapy for treatment of hypercholesterolaemia: a qualitative study

Eur J Cardiovasc Nurs. 2003 Jul;2(2):141-9. doi: 10.1016/S1474-5151(03)00028-8.

Abstract

Background: Health Care Practitioners' attempts to implement secondary prevention targets for coronary heart disease (CHD) may be restricted by low rates of persistence with statin therapy. There is a need to understand why some patients, despite having established CHD and elevated cholesterol, do not comply with their prescribed statin regimen.

Aim: To explore patients' perspectives on compliance with statin therapy.

Setting: Primary care, West of Scotland.

Methods: The research approach was qualitative. Thirty-three patients prescribed statin therapy and identified as having different patterns of compliance (poor moderate and good) were interviewed. The in-depth interviews were conducted on a one to one basis. Patients prescribed statin therapy for less than three months were excluded. Data were analysed thematically with the assistance of QSR Nudist.

Findings: From analysis of the narrative data, two broad categories, i.e. 'Patient-health care provider communication' and 'Health beliefs' were identified. These categories encompassed six main themes: 'Initiation of therapy'; 'Subsequent feedback'; 'Sources of misconceptions'; 'Unconditional acceptance'; 'Conditional acceptance'; 'Deferment and Rejection'. Acceptance of and compliance with statin therapy appeared to be associated with the provision, interpretation and feedback of information during patient-practitioner consultations, and patients' beliefs about personal health status, cholesterol, and recommended cholesterol-lowering strategies.

Conclusions: Patients' beliefs and understanding about cholesterol, and the role of cholesterol modifying strategies should be determined prior to the initiation of therapy and at appropriate intervals thereafter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Communication
  • Feedback, Psychological
  • Female
  • Health Knowledge, Attitudes, Practice
  • Health Status
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Hypercholesterolemia / blood
  • Hypercholesterolemia / diagnosis
  • Hypercholesterolemia / drug therapy*
  • Hypercholesterolemia / psychology*
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care / psychology*
  • Patient Education as Topic / standards
  • Physician-Patient Relations
  • Primary Health Care / standards
  • Qualitative Research
  • Scotland
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors