Our data demonstrate that serum lipid and lipoprotein levels continue to track from childhood into young adulthood. The persistence and clustering of multiple CVD risk factors from childhood to adulthood and the impact of obesity in this regard point to the need for preventive measures aimed at developing healthy lifestyles early in life. Adverse levels of LDL-C in childhood persist over time, progress to adult dyslipidemias, and relate to obesity and hypertension as well. NCEP guidelines which classify CVD risk on the basis of LDL-C level, are helpful in targeting individuals at risk early in life.